Structural-Dynamics and Binding Analysis of RBD from SARS-CoV-2 Variants of Concern (VOCs) and GRP78 Receptor Revealed Basis for Higher Infectivity

Glucose-regulated protein 78 (GRP78) might be a receptor for SARS-CoV-2 to bind and enter the host cell. Recently reported mutations in the spike glycoprotein unique to the receptor-binding domain (RBD) of different variants might increase the binding and pathogenesis. However, it is still not known...

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Detalles Bibliográficos
Autores principales: Khan, Abbas, Mohammad, Anwar, Haq, Inamul, Nasar, Mohammad, Ahmad, Waqar, Yousafi, Qudsia, Suleman, Muhammad, Ahmad, Sajjad, Albutti, Aqel, Khan, Taimoor, Marafie, Sulaiman K., Alshawaf, Eman, Ali, Syed Shujait, Abubaker, Jehad, Wei, Dong-Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619099/
https://www.ncbi.nlm.nih.gov/pubmed/34835456
http://dx.doi.org/10.3390/microorganisms9112331

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619099/
https://www.ncbi.nlm.nih.gov/pubmed/34835456
http://dx.doi.org/10.3390/microorganisms9112331

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