RANK-C Expression Sensitizes ER-Negative, EGFR-Positive Breast Cancer Cells to EGFR-Tyrosine Kinase Inhibitors (TKIs)

Background: We have previously shown that overexpression of RANK-c in ER-negative breast cancer cell lines attenuates aggressive properties of cancer cells, partially through a RANK-c/EGFR interaction. EGFR inhibition through TKIs in breast cancer has been tested in triple-negative disease settings...

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Detalles Bibliográficos
Autores principales: Sirinian, Chaido, Papanastasiou, Anastasios D., Degn, Soren E., Frantzi, Theodora, Aronis, Christos, Chaniotis, Dimitrios, Makatsoris, Thomas, Koutras, Angelos, Kalofonos, Haralabos P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619104/
https://www.ncbi.nlm.nih.gov/pubmed/34828291
http://dx.doi.org/10.3390/genes12111686

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