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Seroprevalence of SARS-CoV-2 in a Large Cohort of Italian Police Officers

Certain professional categories are at a high occupational exposure to COVID-19. The aim of this survey was to quantify the seroprevalence of SARS-CoV-2 among police officers in Italy and identify its correlates. In this cross-sectional study, a nationally representative sample of State police emplo...

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Autores principales: Garbarino, Sergio, Domnich, Alexander, Costa, Elisabetta, Giberti, Irene, Mosca, Stefano, Belfiore, Cristiano, Ciprani, Fabrizio, Icardi, Giancarlo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619349/
https://www.ncbi.nlm.nih.gov/pubmed/34831958
http://dx.doi.org/10.3390/ijerph182212201
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author Garbarino, Sergio
Domnich, Alexander
Costa, Elisabetta
Giberti, Irene
Mosca, Stefano
Belfiore, Cristiano
Ciprani, Fabrizio
Icardi, Giancarlo
author_facet Garbarino, Sergio
Domnich, Alexander
Costa, Elisabetta
Giberti, Irene
Mosca, Stefano
Belfiore, Cristiano
Ciprani, Fabrizio
Icardi, Giancarlo
author_sort Garbarino, Sergio
collection PubMed
description Certain professional categories are at a high occupational exposure to COVID-19. The aim of this survey was to quantify the seroprevalence of SARS-CoV-2 among police officers in Italy and identify its correlates. In this cross-sectional study, a nationally representative sample of State police employees was tested for IgG and IgM before the start of the National vaccination campaign. A total of 10,535 subjects (approximately 10% of the total workforce) participated in the study. The overall seroprevalence was 4.8% (95% CI: 4.4–5.3%). However, seropositivity was unevenly distributed across the country with a clear (p < 0.001) North–South gradient. In particular, the seroprevalence was 5.6 times higher in northern regions than in southern regions (9.0% vs. 1.6%). Most (71.2%) seropositive subjects reported having no recent symptoms potentially attributable to SARS-CoV-2 infection. Previous dysosmia, dysgeusia, and influenza-like illness symptoms were positive predictors of being seropositive. However, the prognostic value of dysosmia depended (p < 0.05) on both sex and prior influenza-like illness. The baseline seroprevalence of SARS-CoV-2 in police employees is considerable. A significant risk of occupational exposure, frequent asymptomatic cases and the progressive waning of neutralizing antibodies suggest that the police workers should be considered among the job categories prioritized for the booster COVID-19 vaccine dose.
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spelling pubmed-86193492021-11-27 Seroprevalence of SARS-CoV-2 in a Large Cohort of Italian Police Officers Garbarino, Sergio Domnich, Alexander Costa, Elisabetta Giberti, Irene Mosca, Stefano Belfiore, Cristiano Ciprani, Fabrizio Icardi, Giancarlo Int J Environ Res Public Health Article Certain professional categories are at a high occupational exposure to COVID-19. The aim of this survey was to quantify the seroprevalence of SARS-CoV-2 among police officers in Italy and identify its correlates. In this cross-sectional study, a nationally representative sample of State police employees was tested for IgG and IgM before the start of the National vaccination campaign. A total of 10,535 subjects (approximately 10% of the total workforce) participated in the study. The overall seroprevalence was 4.8% (95% CI: 4.4–5.3%). However, seropositivity was unevenly distributed across the country with a clear (p < 0.001) North–South gradient. In particular, the seroprevalence was 5.6 times higher in northern regions than in southern regions (9.0% vs. 1.6%). Most (71.2%) seropositive subjects reported having no recent symptoms potentially attributable to SARS-CoV-2 infection. Previous dysosmia, dysgeusia, and influenza-like illness symptoms were positive predictors of being seropositive. However, the prognostic value of dysosmia depended (p < 0.05) on both sex and prior influenza-like illness. The baseline seroprevalence of SARS-CoV-2 in police employees is considerable. A significant risk of occupational exposure, frequent asymptomatic cases and the progressive waning of neutralizing antibodies suggest that the police workers should be considered among the job categories prioritized for the booster COVID-19 vaccine dose. MDPI 2021-11-20 /pmc/articles/PMC8619349/ /pubmed/34831958 http://dx.doi.org/10.3390/ijerph182212201 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Garbarino, Sergio
Domnich, Alexander
Costa, Elisabetta
Giberti, Irene
Mosca, Stefano
Belfiore, Cristiano
Ciprani, Fabrizio
Icardi, Giancarlo
Seroprevalence of SARS-CoV-2 in a Large Cohort of Italian Police Officers
title Seroprevalence of SARS-CoV-2 in a Large Cohort of Italian Police Officers
title_full Seroprevalence of SARS-CoV-2 in a Large Cohort of Italian Police Officers
title_fullStr Seroprevalence of SARS-CoV-2 in a Large Cohort of Italian Police Officers
title_full_unstemmed Seroprevalence of SARS-CoV-2 in a Large Cohort of Italian Police Officers
title_short Seroprevalence of SARS-CoV-2 in a Large Cohort of Italian Police Officers
title_sort seroprevalence of sars-cov-2 in a large cohort of italian police officers
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619349/
https://www.ncbi.nlm.nih.gov/pubmed/34831958
http://dx.doi.org/10.3390/ijerph182212201
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