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Analysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus
Background and Objectives: Gestational diabetes mellitus (GDM) represents one of the most common complications during pregnancy, being associated with numerous maternal and neonatal complications. The study aimed to analyze maternal and neonatal complications associated with GDM. The risk factors of...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619358/ https://www.ncbi.nlm.nih.gov/pubmed/34833388 http://dx.doi.org/10.3390/medicina57111170 |
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author | Preda, Agnesa Pădureanu, Vlad Moța, Maria Ștefan, Adela-Gabriela Comănescu, Alexandru Cristian Radu, Lucrețiu Mazilu, Emilia Roxana Vladu, Ionela Mihaela |
author_facet | Preda, Agnesa Pădureanu, Vlad Moța, Maria Ștefan, Adela-Gabriela Comănescu, Alexandru Cristian Radu, Lucrețiu Mazilu, Emilia Roxana Vladu, Ionela Mihaela |
author_sort | Preda, Agnesa |
collection | PubMed |
description | Background and Objectives: Gestational diabetes mellitus (GDM) represents one of the most common complications during pregnancy, being associated with numerous maternal and neonatal complications. The study aimed to analyze maternal and neonatal complications associated with GDM. The risk factors of GDM and of the maternal and neonatal complications were studied in order to prevent their occurrence. Materials and Methods: The study included 97 women in the study, who underwent an oral glucose tolerance test (OGTT) between weeks 24–28 of pregnancy, consequently being divided into two groups: pregnant women with and without GDM. Statistical analysis was performed using the SPSS 26.0 software and MATLAB fitglm, the results being considered statistically significant if p < 0.05. Results: We observed statistically significant differences between the group of women with and without GDM, regarding gestational hypertension (17.6% vs. 0%), preeclampsia (13.72% vs. 0%), and cesarean delivery (96.1% vs. 78,3%). Data on the newborn and neonatal complications: statistically significant differences were recorded between the two groups (GDM vs. no GDM) regarding the average weight at birth (3339.41 ± 658.12 g vs. 3122.83 ± 173.67 g), presence of large for gestational age (21.6% vs. 0%), macrosomia (13.7% vs. 0%), excessive fetal growth (35.3% vs. 0%), respiratory distress (31.4% vs. 0%), hospitalization for at least 24 h in the Neonatal Intensive Care Unit (9.80% vs. 0%), and APGAR score <7 both 1 and 5 min following birth (7.8% vs. 0%). Additionally, the frequency of neonatal hypoglycemia and hyperbilirubinemia was higher among newborns from mothers with GDM. Conclusions: The screening and diagnosis of GDM is vital, and appropriate management is required for the prevention of maternal and neonatal complications associated with GDM. It is also important to know the risk factors for GDM and attempt to prevent their appearance. |
format | Online Article Text |
id | pubmed-8619358 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86193582021-11-27 Analysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus Preda, Agnesa Pădureanu, Vlad Moța, Maria Ștefan, Adela-Gabriela Comănescu, Alexandru Cristian Radu, Lucrețiu Mazilu, Emilia Roxana Vladu, Ionela Mihaela Medicina (Kaunas) Article Background and Objectives: Gestational diabetes mellitus (GDM) represents one of the most common complications during pregnancy, being associated with numerous maternal and neonatal complications. The study aimed to analyze maternal and neonatal complications associated with GDM. The risk factors of GDM and of the maternal and neonatal complications were studied in order to prevent their occurrence. Materials and Methods: The study included 97 women in the study, who underwent an oral glucose tolerance test (OGTT) between weeks 24–28 of pregnancy, consequently being divided into two groups: pregnant women with and without GDM. Statistical analysis was performed using the SPSS 26.0 software and MATLAB fitglm, the results being considered statistically significant if p < 0.05. Results: We observed statistically significant differences between the group of women with and without GDM, regarding gestational hypertension (17.6% vs. 0%), preeclampsia (13.72% vs. 0%), and cesarean delivery (96.1% vs. 78,3%). Data on the newborn and neonatal complications: statistically significant differences were recorded between the two groups (GDM vs. no GDM) regarding the average weight at birth (3339.41 ± 658.12 g vs. 3122.83 ± 173.67 g), presence of large for gestational age (21.6% vs. 0%), macrosomia (13.7% vs. 0%), excessive fetal growth (35.3% vs. 0%), respiratory distress (31.4% vs. 0%), hospitalization for at least 24 h in the Neonatal Intensive Care Unit (9.80% vs. 0%), and APGAR score <7 both 1 and 5 min following birth (7.8% vs. 0%). Additionally, the frequency of neonatal hypoglycemia and hyperbilirubinemia was higher among newborns from mothers with GDM. Conclusions: The screening and diagnosis of GDM is vital, and appropriate management is required for the prevention of maternal and neonatal complications associated with GDM. It is also important to know the risk factors for GDM and attempt to prevent their appearance. MDPI 2021-10-28 /pmc/articles/PMC8619358/ /pubmed/34833388 http://dx.doi.org/10.3390/medicina57111170 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Preda, Agnesa Pădureanu, Vlad Moța, Maria Ștefan, Adela-Gabriela Comănescu, Alexandru Cristian Radu, Lucrețiu Mazilu, Emilia Roxana Vladu, Ionela Mihaela Analysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus |
title | Analysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus |
title_full | Analysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus |
title_fullStr | Analysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus |
title_full_unstemmed | Analysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus |
title_short | Analysis of Maternal and Neonatal Complications in a Group of Patients with Gestational Diabetes Mellitus |
title_sort | analysis of maternal and neonatal complications in a group of patients with gestational diabetes mellitus |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619358/ https://www.ncbi.nlm.nih.gov/pubmed/34833388 http://dx.doi.org/10.3390/medicina57111170 |
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