Cargando…
Placental mTOR Signaling and Sexual Dimorphism in Metabolic Health across the Lifespan of Offspring
Robust evidence of fetal programming of adult disease has surfaced in the last several decades. Human and preclinical investigations of intrauterine insults report perturbations in placental nutrient sensing by the mechanistic target of rapamycin (mTOR). This review focuses on pregnancy complication...
Autores principales: | Beetch, Megan, Alejandro, Emilyn U. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619510/ https://www.ncbi.nlm.nih.gov/pubmed/34828683 http://dx.doi.org/10.3390/children8110970 |
Ejemplares similares
-
Impact of placental mTOR deficiency on peripheral insulin signaling in adult mice offspring
por: Beetch, Megan, et al.
Publicado: (2023) -
Placental mTOR complex 1 regulates fetal programming of obesity and insulin resistance in mice
por: Akhaphong, Brian, et al.
Publicado: (2021) -
Placental Insulin Receptor Transiently Regulates Glucose Homeostasis in the Adult Mouse Offspring of Multiparous Dams
por: Chung, Grace, et al.
Publicado: (2022) -
Disruption of O-Linked N-Acetylglucosamine Signaling in Placenta Induces Insulin Sensitivity in Female Offspring
por: Moore, Mackenzie, et al.
Publicado: (2021) -
Nutrient Sensor mTOR and OGT: Orchestrators of Organelle Homeostasis in Pancreatic β-Cells
por: Esch, Nicholas, et al.
Publicado: (2020)