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Natural Apocarotenoids and Their Synthetic Glycopeptide Conjugates Inhibit SARS-CoV-2 Replication

The protracted global COVID-19 pandemic urges the development of new drugs against the causative agent SARS-CoV-2. The clinically used glycopeptide antibiotic, teicoplanin, emerged as a potential antiviral, and its efficacy was improved with lipophilic modifications. This prompted us to prepare new...

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Detalles Bibliográficos
Autores principales: Bereczki, Ilona, Papp, Henrietta, Kuczmog, Anett, Madai, Mónika, Nagy, Veronika, Agócs, Attila, Batta, Gyula, Milánkovits, Márton, Ostorházi, Eszter, Mitrović, Ana, Kos, Janko, Zsigmond, Áron, Hajdú, István, Lőrincz, Zsolt, Bajusz, Dávid, Keserű, György Miklós, Hodek, Jan, Weber, Jan, Jakab, Ferenc, Herczegh, Pál, Borbás, Anikó
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619593/
https://www.ncbi.nlm.nih.gov/pubmed/34832893
http://dx.doi.org/10.3390/ph14111111