Cargando…
Natural Apocarotenoids and Their Synthetic Glycopeptide Conjugates Inhibit SARS-CoV-2 Replication
The protracted global COVID-19 pandemic urges the development of new drugs against the causative agent SARS-CoV-2. The clinically used glycopeptide antibiotic, teicoplanin, emerged as a potential antiviral, and its efficacy was improved with lipophilic modifications. This prompted us to prepare new...
Autores principales: | Bereczki, Ilona, Papp, Henrietta, Kuczmog, Anett, Madai, Mónika, Nagy, Veronika, Agócs, Attila, Batta, Gyula, Milánkovits, Márton, Ostorházi, Eszter, Mitrović, Ana, Kos, Janko, Zsigmond, Áron, Hajdú, István, Lőrincz, Zsolt, Bajusz, Dávid, Keserű, György Miklós, Hodek, Jan, Weber, Jan, Jakab, Ferenc, Herczegh, Pál, Borbás, Anikó |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619593/ https://www.ncbi.nlm.nih.gov/pubmed/34832893 http://dx.doi.org/10.3390/ph14111111 |
Ejemplares similares
-
Semisynthetic teicoplanin derivatives with dual antimicrobial activity against SARS-CoV-2 and multiresistant bacteria
por: Bereczki, Ilona, et al.
Publicado: (2022) -
The First Dimeric Derivatives of the Glycopeptide Antibiotic Teicoplanin
por: Bereczki, Ilona, et al.
Publicado: (2022) -
Synthesis of an amphiphilic vancomycin aglycone derivative inspired by polymyxins: overcoming glycopeptide resistance in Gram-positive and Gram-negative bacteria in synergy with teicoplanin in vitro
por: Szűcs, Zsolt, et al.
Publicado: (2022) -
Synthesis of Antiviral Perfluoroalkyl Derivatives of Teicoplanin and Vancomycin
por: Bereczki, Ilona, et al.
Publicado: (2020) -
The Very First Modification of Pleuromutilin and Lefamulin by Photoinitiated Radical Addition Reactions—Synthesis and Antibacterial Studies
por: Thai Le, Son, et al.
Publicado: (2021)