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Safety and Efficacy of Combined Low-Dose Lithium and Low-Dose Aspirin: A Pharmacological and Behavioral Proof-of-Concept Study in Rats

Despite established efficacy in bipolar disorder patients, lithium (Li) therapy has serious side effects, particularly chronic kidney disease. We examined the safety and behavioral effects of combined chronic low-dose aspirin plus low-dose Li in rats to explore the toxicity and therapeutic potential...

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Detalles Bibliográficos
Autores principales: Shvartsur, Rachel, Agam, Galila, Shnaider, Alla, Uzzan, Sarit, Nassar, Ahmad, Jabarin, Adi, Abu-Freha, Naim, Meir, Karen, Azab, Abed N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619680/
https://www.ncbi.nlm.nih.gov/pubmed/34834241
http://dx.doi.org/10.3390/pharmaceutics13111827