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Efficient Messenger RNA Delivery to the Kidney Using Renal Pelvis Injection in Mice †
Renal dysfunction is often associated with the inflammatory cascade, leading to non-reversible nephrofibrosis. Gene therapy has the ability to treat the pathology. However, the difficulty in introducing genes into the kidney, via either viral vectors or plasmid DNA (pDNA), has hampered its extensive...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619888/ https://www.ncbi.nlm.nih.gov/pubmed/34834225 http://dx.doi.org/10.3390/pharmaceutics13111810 |