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COVEVOL: Natural Evolution at 6 Months of COVID-19
Many studies have investigated post-COVID symptoms, but the predictors of symptom persistence remain unknown. The objective was to describe the natural course of the disease at 6 months and to identify possible factors favoring the resurgence or persistence of these symptoms. COVEVOL is a retrospect...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619893/ https://www.ncbi.nlm.nih.gov/pubmed/34834958 http://dx.doi.org/10.3390/v13112151 |
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author | Messin, Louise Puyraveau, Marc Benabdallah, Yousri Lepiller, Quentin Gendrin, Vincent Zayet, Souheil Klopfenstein, Timothée Toko, Lynda Pierron, Alix Royer, Pierre-Yves |
author_facet | Messin, Louise Puyraveau, Marc Benabdallah, Yousri Lepiller, Quentin Gendrin, Vincent Zayet, Souheil Klopfenstein, Timothée Toko, Lynda Pierron, Alix Royer, Pierre-Yves |
author_sort | Messin, Louise |
collection | PubMed |
description | Many studies have investigated post-COVID symptoms, but the predictors of symptom persistence remain unknown. The objective was to describe the natural course of the disease at 6 months and to identify possible factors favoring the resurgence or persistence of these symptoms. COVEVOL is a retrospective observational descriptive study of 74 patients. All patients with positive SARS-CoV-2 PCR from March 2020 were included. We compared a group with symptom persistence (PS group) with another group without symptom persistence (no-PS group). Fifty-three out of seventy-four patients (71.62%) described at least one persistent symptom at 6 months of SARS-CoV-2 infection. In the PS group, 56.6% were women and the average age was 54.7 years old [21–89.2] ± 16.9. The main symptoms were asthenia (56.6%, n = 30), dyspnea (34%, n = 18), anxiety (32.1% n = 17), anosmia (24.5%, n = 13) and agueusia (15.1% n = 8). Ten patients (13.51%) presented a resurgence in symptoms. Patients in the PS group were older (p = 0.0048), had a higher BMI (p = 0.0071), and were more frequently hospitalized (p = 0.0359) compared to the no-PS group. Odynophagia and nasal obstruction were less present in the inaugural symptoms of COVID-19 in the PS group (p = 0.0202 and p = 0.0332). Persistent post-COVID syndromes are common and identification of contributing factors is necessary for understanding this phenomenon and appropriate management. |
format | Online Article Text |
id | pubmed-8619893 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86198932021-11-27 COVEVOL: Natural Evolution at 6 Months of COVID-19 Messin, Louise Puyraveau, Marc Benabdallah, Yousri Lepiller, Quentin Gendrin, Vincent Zayet, Souheil Klopfenstein, Timothée Toko, Lynda Pierron, Alix Royer, Pierre-Yves Viruses Article Many studies have investigated post-COVID symptoms, but the predictors of symptom persistence remain unknown. The objective was to describe the natural course of the disease at 6 months and to identify possible factors favoring the resurgence or persistence of these symptoms. COVEVOL is a retrospective observational descriptive study of 74 patients. All patients with positive SARS-CoV-2 PCR from March 2020 were included. We compared a group with symptom persistence (PS group) with another group without symptom persistence (no-PS group). Fifty-three out of seventy-four patients (71.62%) described at least one persistent symptom at 6 months of SARS-CoV-2 infection. In the PS group, 56.6% were women and the average age was 54.7 years old [21–89.2] ± 16.9. The main symptoms were asthenia (56.6%, n = 30), dyspnea (34%, n = 18), anxiety (32.1% n = 17), anosmia (24.5%, n = 13) and agueusia (15.1% n = 8). Ten patients (13.51%) presented a resurgence in symptoms. Patients in the PS group were older (p = 0.0048), had a higher BMI (p = 0.0071), and were more frequently hospitalized (p = 0.0359) compared to the no-PS group. Odynophagia and nasal obstruction were less present in the inaugural symptoms of COVID-19 in the PS group (p = 0.0202 and p = 0.0332). Persistent post-COVID syndromes are common and identification of contributing factors is necessary for understanding this phenomenon and appropriate management. MDPI 2021-10-25 /pmc/articles/PMC8619893/ /pubmed/34834958 http://dx.doi.org/10.3390/v13112151 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Messin, Louise Puyraveau, Marc Benabdallah, Yousri Lepiller, Quentin Gendrin, Vincent Zayet, Souheil Klopfenstein, Timothée Toko, Lynda Pierron, Alix Royer, Pierre-Yves COVEVOL: Natural Evolution at 6 Months of COVID-19 |
title | COVEVOL: Natural Evolution at 6 Months of COVID-19 |
title_full | COVEVOL: Natural Evolution at 6 Months of COVID-19 |
title_fullStr | COVEVOL: Natural Evolution at 6 Months of COVID-19 |
title_full_unstemmed | COVEVOL: Natural Evolution at 6 Months of COVID-19 |
title_short | COVEVOL: Natural Evolution at 6 Months of COVID-19 |
title_sort | covevol: natural evolution at 6 months of covid-19 |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619893/ https://www.ncbi.nlm.nih.gov/pubmed/34834958 http://dx.doi.org/10.3390/v13112151 |
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