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Ketamine—New Possibilities in the Treatment of Depression: A Narrative Review

The SARS-CoV-2 coronavirus epidemic has led to an increase in the number of people with depression. Symptoms related to the mental sphere (mainly depression and anxiety) may be experienced by one third of the worldwide population. This entails the need for the effective and rapid treatment of depres...

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Detalles Bibliográficos
Autores principales: Kowalczyk, Mateusz, Kowalczyk, Edward, Kwiatkowski, Paweł, Łopusiewicz, Łukasz, Sienkiewicz, Monika, Talarowska, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619908/
https://www.ncbi.nlm.nih.gov/pubmed/34833062
http://dx.doi.org/10.3390/life11111186
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author Kowalczyk, Mateusz
Kowalczyk, Edward
Kwiatkowski, Paweł
Łopusiewicz, Łukasz
Sienkiewicz, Monika
Talarowska, Monika
author_facet Kowalczyk, Mateusz
Kowalczyk, Edward
Kwiatkowski, Paweł
Łopusiewicz, Łukasz
Sienkiewicz, Monika
Talarowska, Monika
author_sort Kowalczyk, Mateusz
collection PubMed
description The SARS-CoV-2 coronavirus epidemic has led to an increase in the number of people with depression. Symptoms related to the mental sphere (mainly depression and anxiety) may be experienced by one third of the worldwide population. This entails the need for the effective and rapid treatment of depressive episodes. An effective drug seems to be s-ketamine, which was accepted in March 2019 by the Food and Drug Administration (FDA) for the treatment of drug-resistant depression. This drug provides a quick antidepressant effect with maximum effectiveness achieved after 24 h. It also appears to reduce the occurrence of suicidal thoughts. However, research into undesirable effects, especially in groups of people susceptible to psychotic episodes or those who use alcohol or psychoactive substances, is necessary.
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spelling pubmed-86199082021-11-27 Ketamine—New Possibilities in the Treatment of Depression: A Narrative Review Kowalczyk, Mateusz Kowalczyk, Edward Kwiatkowski, Paweł Łopusiewicz, Łukasz Sienkiewicz, Monika Talarowska, Monika Life (Basel) Review The SARS-CoV-2 coronavirus epidemic has led to an increase in the number of people with depression. Symptoms related to the mental sphere (mainly depression and anxiety) may be experienced by one third of the worldwide population. This entails the need for the effective and rapid treatment of depressive episodes. An effective drug seems to be s-ketamine, which was accepted in March 2019 by the Food and Drug Administration (FDA) for the treatment of drug-resistant depression. This drug provides a quick antidepressant effect with maximum effectiveness achieved after 24 h. It also appears to reduce the occurrence of suicidal thoughts. However, research into undesirable effects, especially in groups of people susceptible to psychotic episodes or those who use alcohol or psychoactive substances, is necessary. MDPI 2021-11-05 /pmc/articles/PMC8619908/ /pubmed/34833062 http://dx.doi.org/10.3390/life11111186 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Kowalczyk, Mateusz
Kowalczyk, Edward
Kwiatkowski, Paweł
Łopusiewicz, Łukasz
Sienkiewicz, Monika
Talarowska, Monika
Ketamine—New Possibilities in the Treatment of Depression: A Narrative Review
title Ketamine—New Possibilities in the Treatment of Depression: A Narrative Review
title_full Ketamine—New Possibilities in the Treatment of Depression: A Narrative Review
title_fullStr Ketamine—New Possibilities in the Treatment of Depression: A Narrative Review
title_full_unstemmed Ketamine—New Possibilities in the Treatment of Depression: A Narrative Review
title_short Ketamine—New Possibilities in the Treatment of Depression: A Narrative Review
title_sort ketamine—new possibilities in the treatment of depression: a narrative review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619908/
https://www.ncbi.nlm.nih.gov/pubmed/34833062
http://dx.doi.org/10.3390/life11111186
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