Targeting HER2 Expressing Tumors with a Potent Drug Conjugate Based on an Albumin Binding Domain-Derived Affinity Protein

Albumin binding domain derived affinity proteins (ADAPTs) are a class of small and folded engineered scaffold proteins that holds great promise for targeting cancer tumors. Here, we have extended the in vivo half-life of an ADAPT, targeting the human epidermal growth factor receptor 2 (HER2) by fusi...

Descripción completa

Detalles Bibliográficos
Autores principales: Garousi, Javad, Ding, Haozhong, von Witting, Emma, Xu, Tianqi, Vorobyeva, Anzhelika, Oroujeni, Maryam, Orlova, Anna, Hober, Sophia, Gräslund, Torbjörn, Tolmachev, Vladimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619933/
https://www.ncbi.nlm.nih.gov/pubmed/34834262
http://dx.doi.org/10.3390/pharmaceutics13111847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619933/
https://www.ncbi.nlm.nih.gov/pubmed/34834262
http://dx.doi.org/10.3390/pharmaceutics13111847

Ejemplares similares