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Targeting HER2 Expressing Tumors with a Potent Drug Conjugate Based on an Albumin Binding Domain-Derived Affinity Protein

Albumin binding domain derived affinity proteins (ADAPTs) are a class of small and folded engineered scaffold proteins that holds great promise for targeting cancer tumors. Here, we have extended the in vivo half-life of an ADAPT, targeting the human epidermal growth factor receptor 2 (HER2) by fusi...

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Detalles Bibliográficos
Autores principales:	Garousi, Javad, Ding, Haozhong, von Witting, Emma, Xu, Tianqi, Vorobyeva, Anzhelika, Oroujeni, Maryam, Orlova, Anna, Hober, Sophia, Gräslund, Torbjörn, Tolmachev, Vladimir
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619933/ https://www.ncbi.nlm.nih.gov/pubmed/34834262 http://dx.doi.org/10.3390/pharmaceutics13111847

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