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T Cell Bispecific Antibodies: An Antibody-Based Delivery System for Inducing Antitumor Immunity

As a breakthrough immunotherapy, T cell bispecific antibodies (T-BsAbs) are a promising antibody therapy for various kinds of cancer. In general, T-BsAbs have dual-binding specificity to a tumor-associated antigen and a CD3 subunit forming a complex with the TCR. This enables T-BsAbs to crosslink tu...

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Detalles Bibliográficos
Autores principales: Kamakura, Daisuke, Asano, Ryutaro, Yasunaga, Masahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619951/
https://www.ncbi.nlm.nih.gov/pubmed/34832954
http://dx.doi.org/10.3390/ph14111172