Cargando…
Programmed Intermittent Epidural Bolus versus Continuous Epidural Infusion in Major Upper Abdominal Surgery: A Retrospective Comparative Study
Although recent evidence shows that the programmed intermittent epidural bolus can provide improved analgesia compared to continuous epidural infusion during labor, its usefulness in major upper abdominal surgery remains unclear. We evaluated the effect of programmed intermittent epidural bolus vers...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619973/ https://www.ncbi.nlm.nih.gov/pubmed/34830661 http://dx.doi.org/10.3390/jcm10225382 |
_version_ | 1784605113141166080 |
---|---|
author | Kim, Yeon-Ju Lee, Do-Kyeong Kwon, Hyun-Jung Kwon, Hye-Mee Lee, Jong-Hyuk Kim, Doo-Hwan Jeong, Sung-Moon |
author_facet | Kim, Yeon-Ju Lee, Do-Kyeong Kwon, Hyun-Jung Kwon, Hye-Mee Lee, Jong-Hyuk Kim, Doo-Hwan Jeong, Sung-Moon |
author_sort | Kim, Yeon-Ju |
collection | PubMed |
description | Although recent evidence shows that the programmed intermittent epidural bolus can provide improved analgesia compared to continuous epidural infusion during labor, its usefulness in major upper abdominal surgery remains unclear. We evaluated the effect of programmed intermittent epidural bolus versus continuous epidural infusion on the consumption of postoperative rescue opioids, pain intensity, and consumption of local anesthetic by retrospective analysis of data of patients who underwent major upper abdominal surgery under ultrasound-assisted thoracic epidural analgesia between July 2018 and October 2020. The primary outcome was total opioid consumption up to 72 h after surgery. The data of postoperative pain scores, epidural local anesthetic consumption, and adverse events from 193 patients were analyzed (continuous epidural infusion: n = 124, programmed intermittent epidural bolus: n = 69). There was no significant difference in the rescue opioid consumption in the 72 h postoperative period between the groups (33.3 mg [20.0–43.3] vs. 28.3 mg [18.3–43.3], p = 0.375). There were also no significant differences in the pain scores, epidural local anesthetic consumption, and incidence of adverse events. Our findings suggest that the quality of postoperative analgesia and safety following major upper abdominal surgery were comparable between the groups. However, the use of programmed intermittent epidural bolus requires further evaluation. |
format | Online Article Text |
id | pubmed-8619973 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86199732021-11-27 Programmed Intermittent Epidural Bolus versus Continuous Epidural Infusion in Major Upper Abdominal Surgery: A Retrospective Comparative Study Kim, Yeon-Ju Lee, Do-Kyeong Kwon, Hyun-Jung Kwon, Hye-Mee Lee, Jong-Hyuk Kim, Doo-Hwan Jeong, Sung-Moon J Clin Med Article Although recent evidence shows that the programmed intermittent epidural bolus can provide improved analgesia compared to continuous epidural infusion during labor, its usefulness in major upper abdominal surgery remains unclear. We evaluated the effect of programmed intermittent epidural bolus versus continuous epidural infusion on the consumption of postoperative rescue opioids, pain intensity, and consumption of local anesthetic by retrospective analysis of data of patients who underwent major upper abdominal surgery under ultrasound-assisted thoracic epidural analgesia between July 2018 and October 2020. The primary outcome was total opioid consumption up to 72 h after surgery. The data of postoperative pain scores, epidural local anesthetic consumption, and adverse events from 193 patients were analyzed (continuous epidural infusion: n = 124, programmed intermittent epidural bolus: n = 69). There was no significant difference in the rescue opioid consumption in the 72 h postoperative period between the groups (33.3 mg [20.0–43.3] vs. 28.3 mg [18.3–43.3], p = 0.375). There were also no significant differences in the pain scores, epidural local anesthetic consumption, and incidence of adverse events. Our findings suggest that the quality of postoperative analgesia and safety following major upper abdominal surgery were comparable between the groups. However, the use of programmed intermittent epidural bolus requires further evaluation. MDPI 2021-11-18 /pmc/articles/PMC8619973/ /pubmed/34830661 http://dx.doi.org/10.3390/jcm10225382 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Kim, Yeon-Ju Lee, Do-Kyeong Kwon, Hyun-Jung Kwon, Hye-Mee Lee, Jong-Hyuk Kim, Doo-Hwan Jeong, Sung-Moon Programmed Intermittent Epidural Bolus versus Continuous Epidural Infusion in Major Upper Abdominal Surgery: A Retrospective Comparative Study |
title | Programmed Intermittent Epidural Bolus versus Continuous Epidural Infusion in Major Upper Abdominal Surgery: A Retrospective Comparative Study |
title_full | Programmed Intermittent Epidural Bolus versus Continuous Epidural Infusion in Major Upper Abdominal Surgery: A Retrospective Comparative Study |
title_fullStr | Programmed Intermittent Epidural Bolus versus Continuous Epidural Infusion in Major Upper Abdominal Surgery: A Retrospective Comparative Study |
title_full_unstemmed | Programmed Intermittent Epidural Bolus versus Continuous Epidural Infusion in Major Upper Abdominal Surgery: A Retrospective Comparative Study |
title_short | Programmed Intermittent Epidural Bolus versus Continuous Epidural Infusion in Major Upper Abdominal Surgery: A Retrospective Comparative Study |
title_sort | programmed intermittent epidural bolus versus continuous epidural infusion in major upper abdominal surgery: a retrospective comparative study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619973/ https://www.ncbi.nlm.nih.gov/pubmed/34830661 http://dx.doi.org/10.3390/jcm10225382 |
work_keys_str_mv | AT kimyeonju programmedintermittentepiduralbolusversuscontinuousepiduralinfusioninmajorupperabdominalsurgeryaretrospectivecomparativestudy AT leedokyeong programmedintermittentepiduralbolusversuscontinuousepiduralinfusioninmajorupperabdominalsurgeryaretrospectivecomparativestudy AT kwonhyunjung programmedintermittentepiduralbolusversuscontinuousepiduralinfusioninmajorupperabdominalsurgeryaretrospectivecomparativestudy AT kwonhyemee programmedintermittentepiduralbolusversuscontinuousepiduralinfusioninmajorupperabdominalsurgeryaretrospectivecomparativestudy AT leejonghyuk programmedintermittentepiduralbolusversuscontinuousepiduralinfusioninmajorupperabdominalsurgeryaretrospectivecomparativestudy AT kimdoohwan programmedintermittentepiduralbolusversuscontinuousepiduralinfusioninmajorupperabdominalsurgeryaretrospectivecomparativestudy AT jeongsungmoon programmedintermittentepiduralbolusversuscontinuousepiduralinfusioninmajorupperabdominalsurgeryaretrospectivecomparativestudy |