Aspergillus fumigatus Fumagillin Contributes to Host Cell Damage

The activity of fumagillin, a mycotoxin produced by Aspergillus fumigatus, has not been studied in depth. In this study, we used a commercial fumagillin on cultures of two cell types (A549 pneumocytes and RAW 264.7 macrophages). This toxin joins its target, MetAP2 protein, inside cells and, as a res...

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Detalles Bibliográficos
Autores principales: Guruceaga, Xabier, Perez-Cuesta, Uxue, Pellon, Aize, Cendon-Sanchez, Saioa, Pelegri-Martinez, Eduardo, Gonzalez, Oskar, Hernando, Fernando Luis, Mayayo, Emilio, Anguita, Juan, Alonso, Rosa M., Keller, Nancy P., Ramirez-Garcia, Andoni, Rementeria, Aitor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8619997/
https://www.ncbi.nlm.nih.gov/pubmed/34829223
http://dx.doi.org/10.3390/jof7110936

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