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Vitamin D Status of the British African-Caribbean Residents: Analysis of the UK Biobank Cohort
The vitamin D status of the United Kingdom (UK) African-Caribbean (AC) population remains under-researched, despite an increased risk of vitamin D deficiency due to darker skin phenotypes and living at a high latitude. This cross-sectional study explored the vitamin D status and intake of AC individ...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620024/ https://www.ncbi.nlm.nih.gov/pubmed/34836358 http://dx.doi.org/10.3390/nu13114104 |
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author | Vearing, Rebecca M. Hart, Kathryn H. Charlton, Karen Probst, Yasmine Blackbourn, David J. Ahmadi, Kourosh R. Lanham-New, Susan A. Darling, Andrea L. |
author_facet | Vearing, Rebecca M. Hart, Kathryn H. Charlton, Karen Probst, Yasmine Blackbourn, David J. Ahmadi, Kourosh R. Lanham-New, Susan A. Darling, Andrea L. |
author_sort | Vearing, Rebecca M. |
collection | PubMed |
description | The vitamin D status of the United Kingdom (UK) African-Caribbean (AC) population remains under-researched, despite an increased risk of vitamin D deficiency due to darker skin phenotypes and living at a high latitude. This cross-sectional study explored the vitamin D status and intake of AC individuals (n = 4046 with a valid serum 25(OH)D measurement) from the UK Biobank Cohort, aged ≥40 years at baseline (2006–2010). Over one third of the population were deficient (<25 nmol/L), 41.1% were insufficient (25–50 nmol/L) and 15.9% were sufficient (>50 nmol/L). Median (IQR) 25(OH)D was 30.0 (20.9) nmol/L. Logistic regression showed that brown/black skin phenotype, winter blood draw, not consuming oily fish and not using vitamin D supplements predicted increased odds of vitamin D deficiency, whilst older age and a summer or autumn blood draw were significantly associated with reduced odds of vitamin D deficiency. Vitamin D deficiency and insufficiency were prevalent in this AC population and is of considerable concern given the individual and societal implications of increased morbidity. Public health messaging for this group should focus on year-round vitamin D supplementation and increasing intakes of culturally appropriate vitamin D-rich foods. These data also support the urgent requirement for a revised vitamin D RNI for ethnic groups. |
format | Online Article Text |
id | pubmed-8620024 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86200242021-11-27 Vitamin D Status of the British African-Caribbean Residents: Analysis of the UK Biobank Cohort Vearing, Rebecca M. Hart, Kathryn H. Charlton, Karen Probst, Yasmine Blackbourn, David J. Ahmadi, Kourosh R. Lanham-New, Susan A. Darling, Andrea L. Nutrients Article The vitamin D status of the United Kingdom (UK) African-Caribbean (AC) population remains under-researched, despite an increased risk of vitamin D deficiency due to darker skin phenotypes and living at a high latitude. This cross-sectional study explored the vitamin D status and intake of AC individuals (n = 4046 with a valid serum 25(OH)D measurement) from the UK Biobank Cohort, aged ≥40 years at baseline (2006–2010). Over one third of the population were deficient (<25 nmol/L), 41.1% were insufficient (25–50 nmol/L) and 15.9% were sufficient (>50 nmol/L). Median (IQR) 25(OH)D was 30.0 (20.9) nmol/L. Logistic regression showed that brown/black skin phenotype, winter blood draw, not consuming oily fish and not using vitamin D supplements predicted increased odds of vitamin D deficiency, whilst older age and a summer or autumn blood draw were significantly associated with reduced odds of vitamin D deficiency. Vitamin D deficiency and insufficiency were prevalent in this AC population and is of considerable concern given the individual and societal implications of increased morbidity. Public health messaging for this group should focus on year-round vitamin D supplementation and increasing intakes of culturally appropriate vitamin D-rich foods. These data also support the urgent requirement for a revised vitamin D RNI for ethnic groups. MDPI 2021-11-16 /pmc/articles/PMC8620024/ /pubmed/34836358 http://dx.doi.org/10.3390/nu13114104 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Vearing, Rebecca M. Hart, Kathryn H. Charlton, Karen Probst, Yasmine Blackbourn, David J. Ahmadi, Kourosh R. Lanham-New, Susan A. Darling, Andrea L. Vitamin D Status of the British African-Caribbean Residents: Analysis of the UK Biobank Cohort |
title | Vitamin D Status of the British African-Caribbean Residents: Analysis of the UK Biobank Cohort |
title_full | Vitamin D Status of the British African-Caribbean Residents: Analysis of the UK Biobank Cohort |
title_fullStr | Vitamin D Status of the British African-Caribbean Residents: Analysis of the UK Biobank Cohort |
title_full_unstemmed | Vitamin D Status of the British African-Caribbean Residents: Analysis of the UK Biobank Cohort |
title_short | Vitamin D Status of the British African-Caribbean Residents: Analysis of the UK Biobank Cohort |
title_sort | vitamin d status of the british african-caribbean residents: analysis of the uk biobank cohort |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620024/ https://www.ncbi.nlm.nih.gov/pubmed/34836358 http://dx.doi.org/10.3390/nu13114104 |
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