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Direct RNA Sequencing Reveals SARS-CoV-2 m6A Sites and Possible Differential DRACH Motif Methylation among Variants
The causative agent of COVID-19 pandemic, SARS-CoV-2, has a 29,903 bases positive-sense single-stranded RNA genome. RNAs exhibit about 150 modified bases that are essential for proper function. Among internal modified bases, the N(6)-methyladenosine, or m6A, is the most frequent, and is implicated i...
Autores principales: | Campos, João H. C., Maricato, Juliana T., Braconi, Carla T., Antoneli, Fernando, Janini, Luiz Mario R., Briones, Marcelo R. S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620083/ https://www.ncbi.nlm.nih.gov/pubmed/34834915 http://dx.doi.org/10.3390/v13112108 |
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