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Direct RNA Sequencing Reveals SARS-CoV-2 m6A Sites and Possible Differential DRACH Motif Methylation among Variants

The causative agent of COVID-19 pandemic, SARS-CoV-2, has a 29,903 bases positive-sense single-stranded RNA genome. RNAs exhibit about 150 modified bases that are essential for proper function. Among internal modified bases, the N(6)-methyladenosine, or m6A, is the most frequent, and is implicated i...

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Detalles Bibliográficos
Autores principales:	Campos, João H. C., Maricato, Juliana T., Braconi, Carla T., Antoneli, Fernando, Janini, Luiz Mario R., Briones, Marcelo R. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620083/ https://www.ncbi.nlm.nih.gov/pubmed/34834915 http://dx.doi.org/10.3390/v13112108

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