Cargando…

Concentration Effect over Thermoresponse Derived from Organometallic Compounds of Functionalized Poly(N-isopropylacrylamide-co-dopamine Methacrylamide)

The functionalization of smart polymers is opening a new perspective in catalysis, drug carriers and biosensors, due to the fact that they can modulate the response regarding conventional devices. This smart response could be affected by the presence of organometallic complexes in terms of interacti...

Descripción completa

Detalles Bibliográficos
Autores principales: Moral-Zamorano, María, Quijada-Garrido, Isabel, San-Miguel, Verónica, Serrano, Berna, Baselga, Juan, Hashmi, Saud, Stadler, Florian J., García-Peñas, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620241/
https://www.ncbi.nlm.nih.gov/pubmed/34833220
http://dx.doi.org/10.3390/polym13223921
_version_ 1784605172203257856
author Moral-Zamorano, María
Quijada-Garrido, Isabel
San-Miguel, Verónica
Serrano, Berna
Baselga, Juan
Hashmi, Saud
Stadler, Florian J.
García-Peñas, Alberto
author_facet Moral-Zamorano, María
Quijada-Garrido, Isabel
San-Miguel, Verónica
Serrano, Berna
Baselga, Juan
Hashmi, Saud
Stadler, Florian J.
García-Peñas, Alberto
author_sort Moral-Zamorano, María
collection PubMed
description The functionalization of smart polymers is opening a new perspective in catalysis, drug carriers and biosensors, due to the fact that they can modulate the response regarding conventional devices. This smart response could be affected by the presence of organometallic complexes in terms of interactions which could affect the physical chemical properties. In this sense, the thermoresponsive behavior of copolymers based on N-isopropylacrylamide (NIPAM) could be affected due to the presence of hydrophobic groups and concentration effect. In this work, the functionalization of a copolymer based on NIPAM and dopamine methacrylamide with different amounts of bis(cyclopentadienyl)titanium (IV) dichloride was carried out. The resulting materials were characterized, showing a clear idea about the mechanism of functionalization through FTIR spectroscopy. The thermoresponsive behavior was also studied for various polymeric solutions in water by UV–vis spectroscopy and calorimetry. The hydrophobic interactions promoted by the organometallic complex could affect the transition associated with the lower critical solution temperature (LCST), specifically, the segments composed by pure NIPAM. That fact would explain the reduction of the width of the LCST-transition, contrary to what could be expected. In addition, the hydrophobicity was tested by the contact angle and also DNA interactions.
format Online
Article
Text
id pubmed-8620241
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-86202412021-11-27 Concentration Effect over Thermoresponse Derived from Organometallic Compounds of Functionalized Poly(N-isopropylacrylamide-co-dopamine Methacrylamide) Moral-Zamorano, María Quijada-Garrido, Isabel San-Miguel, Verónica Serrano, Berna Baselga, Juan Hashmi, Saud Stadler, Florian J. García-Peñas, Alberto Polymers (Basel) Article The functionalization of smart polymers is opening a new perspective in catalysis, drug carriers and biosensors, due to the fact that they can modulate the response regarding conventional devices. This smart response could be affected by the presence of organometallic complexes in terms of interactions which could affect the physical chemical properties. In this sense, the thermoresponsive behavior of copolymers based on N-isopropylacrylamide (NIPAM) could be affected due to the presence of hydrophobic groups and concentration effect. In this work, the functionalization of a copolymer based on NIPAM and dopamine methacrylamide with different amounts of bis(cyclopentadienyl)titanium (IV) dichloride was carried out. The resulting materials were characterized, showing a clear idea about the mechanism of functionalization through FTIR spectroscopy. The thermoresponsive behavior was also studied for various polymeric solutions in water by UV–vis spectroscopy and calorimetry. The hydrophobic interactions promoted by the organometallic complex could affect the transition associated with the lower critical solution temperature (LCST), specifically, the segments composed by pure NIPAM. That fact would explain the reduction of the width of the LCST-transition, contrary to what could be expected. In addition, the hydrophobicity was tested by the contact angle and also DNA interactions. MDPI 2021-11-12 /pmc/articles/PMC8620241/ /pubmed/34833220 http://dx.doi.org/10.3390/polym13223921 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Moral-Zamorano, María
Quijada-Garrido, Isabel
San-Miguel, Verónica
Serrano, Berna
Baselga, Juan
Hashmi, Saud
Stadler, Florian J.
García-Peñas, Alberto
Concentration Effect over Thermoresponse Derived from Organometallic Compounds of Functionalized Poly(N-isopropylacrylamide-co-dopamine Methacrylamide)
title Concentration Effect over Thermoresponse Derived from Organometallic Compounds of Functionalized Poly(N-isopropylacrylamide-co-dopamine Methacrylamide)
title_full Concentration Effect over Thermoresponse Derived from Organometallic Compounds of Functionalized Poly(N-isopropylacrylamide-co-dopamine Methacrylamide)
title_fullStr Concentration Effect over Thermoresponse Derived from Organometallic Compounds of Functionalized Poly(N-isopropylacrylamide-co-dopamine Methacrylamide)
title_full_unstemmed Concentration Effect over Thermoresponse Derived from Organometallic Compounds of Functionalized Poly(N-isopropylacrylamide-co-dopamine Methacrylamide)
title_short Concentration Effect over Thermoresponse Derived from Organometallic Compounds of Functionalized Poly(N-isopropylacrylamide-co-dopamine Methacrylamide)
title_sort concentration effect over thermoresponse derived from organometallic compounds of functionalized poly(n-isopropylacrylamide-co-dopamine methacrylamide)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620241/
https://www.ncbi.nlm.nih.gov/pubmed/34833220
http://dx.doi.org/10.3390/polym13223921
work_keys_str_mv AT moralzamoranomaria concentrationeffectoverthermoresponsederivedfromorganometalliccompoundsoffunctionalizedpolynisopropylacrylamidecodopaminemethacrylamide
AT quijadagarridoisabel concentrationeffectoverthermoresponsederivedfromorganometalliccompoundsoffunctionalizedpolynisopropylacrylamidecodopaminemethacrylamide
AT sanmiguelveronica concentrationeffectoverthermoresponsederivedfromorganometalliccompoundsoffunctionalizedpolynisopropylacrylamidecodopaminemethacrylamide
AT serranoberna concentrationeffectoverthermoresponsederivedfromorganometalliccompoundsoffunctionalizedpolynisopropylacrylamidecodopaminemethacrylamide
AT baselgajuan concentrationeffectoverthermoresponsederivedfromorganometalliccompoundsoffunctionalizedpolynisopropylacrylamidecodopaminemethacrylamide
AT hashmisaud concentrationeffectoverthermoresponsederivedfromorganometalliccompoundsoffunctionalizedpolynisopropylacrylamidecodopaminemethacrylamide
AT stadlerflorianj concentrationeffectoverthermoresponsederivedfromorganometalliccompoundsoffunctionalizedpolynisopropylacrylamidecodopaminemethacrylamide
AT garciapenasalberto concentrationeffectoverthermoresponsederivedfromorganometalliccompoundsoffunctionalizedpolynisopropylacrylamidecodopaminemethacrylamide