MEKK5 Interacts with and Negatively Regulates the E3 Ubiquitin Ligase NEDD4 for Mediating Lung Cancer Cell Migration

Our previous studies have shown that the HECT E3 ubiquitin ligase NEDD4 and kinase MEKK5 both play an essential role in lung cancer migration. A report predicts that MEKK5 may be ubiquitinated by NEDD4; however, interaction of MEKK5 with NEDD4 and ubiquitination of MEKK5 by NEDD4 have not been chara...

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Detalles Bibliográficos
Autores principales: Sun, Aiqin, Zhu, Jun, Xia, Song, Li, Yanling, Wu, Tiantian, Shao, Genbao, Yang, Wannian, Lin, Qiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620495/
https://www.ncbi.nlm.nih.gov/pubmed/34833029
http://dx.doi.org/10.3390/life11111153

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