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Identification and Characterization of a Novel Epitope of ASFV-Encoded dUTPase by Monoclonal Antibodies

Deoxyuridine 5′-triphosphate nucleotidohydrolase (dUTPase) of African swine fever virus (ASFV) is an essential enzyme required for efficient virus replication. Previous crystallography data have indicated that dUTPase (E165R) may serve as a therapeutic target for inhibiting ASFV replication; however...

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Detalles Bibliográficos
Autores principales: Zhang, Shuai, Wang, Rui, Zhu, Xiaojing, Jin, Jiaxin, Lu, Wenlong, Zhao, Xuyang, Wan, Bo, Liao, Yifei, Zhao, Qin, Netherton, Christopher L., Zhuang, Guoqing, Sun, Aijun, Zhang, Gaiping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620545/
https://www.ncbi.nlm.nih.gov/pubmed/34834981
http://dx.doi.org/10.3390/v13112175