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Upregulation of TRPC5 in hippocampal excitatory synapses improves memory impairment associated with neuroinflammation in microglia knockout IL-10 mice

BACKGROUND: Members of the transient receptor potential canonical (TRPC) protein family are widely distributed in the hippocampus of mammals and exert respective and cooperative influences on the functions of neurons. The relationship between specific TRPC subtypes and neuroinflammation is receiving...

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Detalles Bibliográficos
Autores principales: Huo, Shiji, Ren, Jiling, Ma, Yunqing, Ozathaley, Ahsawle, Yuan, Wenjian, Ni, Hong, Li, Dong, Liu, Zhaowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620645/
https://www.ncbi.nlm.nih.gov/pubmed/34836549
http://dx.doi.org/10.1186/s12974-021-02321-w