Selective CNS Targeting and Distribution with a Refined Region-Specific Intranasal Delivery Technique via the Olfactory Mucosa

Intranasal drug delivery is a promising approach for the delivery of drugs to the CNS, but too heterogenous, unprecise delivery methods without standardization decrease the quality of many studies in rodents. Thus, the lack of a precise and region-specific application technique for mice is a major d...

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Detalles Bibliográficos
Autores principales: Maigler, Frank, Ladel, Simone, Flamm, Johannes, Gänger, Stella, Kurpiers, Barbara, Kiderlen, Stefanie, Völk, Ronja, Hamp, Carmen, Hartung, Sunniva, Spiegel, Sebastian, Soleimanizadeh, Arghavan, Eberle, Katharina, Hermann, Rebecca, Krainer, Lukas, Pitzer, Claudia, Schindowski, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620656/
https://www.ncbi.nlm.nih.gov/pubmed/34834319
http://dx.doi.org/10.3390/pharmaceutics13111904

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