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Early upregulation of cytosolic phospholipase A(2)α in motor neurons is induced by misfolded SOD1 in a mouse model of amyotrophic lateral sclerosis

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal multifactorial neurodegenerative disease characterized by the selective death of motor neurons. Cytosolic phospholipase A(2) alpha (cPLA(2)α) upregulation and activation in the spinal cord of ALS patients has been reported. We have previousl...

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Detalles Bibliográficos
Autores principales:	Malada Edelstein, Yafa Fetfet, Solomonov, Yulia, Hadad, Nurit, Alfahel, Leenor, Israelson, Adrian, Levy, Rachel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620709/ https://www.ncbi.nlm.nih.gov/pubmed/34823547 http://dx.doi.org/10.1186/s12974-021-02326-5

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