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Mechanisms of Nucleosome Reorganization by PARP1

Poly(ADP-ribose) polymerase 1 (PARP1) is an enzyme involved in DNA repair, chromatin organization and transcription. During transcription initiation, PARP1 interacts with gene promoters where it binds to nucleosomes, replaces linker histone H1 and participates in gene regulation. However, the mechan...

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Detalles Bibliográficos
Autores principales: Maluchenko, Natalya V., Nilov, Dmitry K., Pushkarev, Sergey V., Kotova, Elena Y., Gerasimova, Nadezhda S., Kirpichnikov, Mikhail P., Langelier, Marie-France, Pascal, John M., Akhtar, Md. Sohail, Feofanov, Alexey V., Studitsky, Vasily M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620739/
https://www.ncbi.nlm.nih.gov/pubmed/34830005
http://dx.doi.org/10.3390/ijms222212127

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