Studies of Potency and Efficacy of an Optimized Artemisinin-Quinoline Hybrid against Multiple Stages of the Plasmodium Life Cycle

A recently developed artemisinin-quinoline hybrid, named 163A, has been shown to display potent activity against the asexual blood stage of Plasmodium, the malaria parasite. In this study, we determined its in vitro cytotoxicity to mammalian cells, its potency to suppress P. berghei hepatic infectio...

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Detalles Bibliográficos
Autores principales: Quadros, Helenita C., Çapcı, Aysun, Herrmann, Lars, D’Alessandro, Sarah, Fontinha, Diana, Azevedo, Raquel, Villarreal, Wilmer, Basilico, Nicoletta, Prudêncio, Miguel, Tsogoeva, Svetlana B., Moreira, Diogo R. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620906/
https://www.ncbi.nlm.nih.gov/pubmed/34832911
http://dx.doi.org/10.3390/ph14111129

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620906/
https://www.ncbi.nlm.nih.gov/pubmed/34832911
http://dx.doi.org/10.3390/ph14111129

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