A familiar study on self-limited childhood epilepsy patients using hIPSC-derived neurons shows a bias towards immaturity at the morphological, electrophysiological and gene expression levels

BACKGROUND: Self-limited Childhood Epilepsies are the most prevalent epileptic syndrome in children. Its pathogenesis is unknown. In this disease, symptoms resolve spontaneously in approximately 50% of patients when maturity is reached, prompting to a maturation problem. The purpose of this study wa...

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Detalles Bibliográficos
Autores principales: Casalia, Mariana L., Casabona, Juan Cruz, García, Corina, Cavaliere Candedo, Verónica, Quintá, Héctor Ramiro, Farías, María Isabel, Gonzalez, Joaquín, Gonzalez Morón, Dolores, Córdoba, Marta, Consalvo, Damian, Mostoslavsky, Gustavo, Urbano, Francisco J., Pasquini, Juana, Murer, Mario Gustavo, Rela, Lorena, Kauffman, Marcelo A., Pitossi, Fernando J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620942/
https://www.ncbi.nlm.nih.gov/pubmed/34823607
http://dx.doi.org/10.1186/s13287-021-02658-2

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