Cargando…

Dietary carbohydrate quality and risk of breast cancer among women

BACKGROUND: A few studies have examined the relationship between carbohydrate quality index (CQI) and risk of breast cancer (BC) among women in Middle Eastern countries. We studied the associations between carbohydrate quality index and the risk of BC in overall and by menopausal status. METHODS: In...

Descripción completa

Detalles Bibliográficos
Autores principales: Sasanfar, Bahareh, Toorang, Fatemeh, Mohebbi, Elham, Zendehdel, Kazem, Azadbakht, Leila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620945/
https://www.ncbi.nlm.nih.gov/pubmed/34823559
http://dx.doi.org/10.1186/s12937-021-00752-y
_version_ 1784605339083079680
author Sasanfar, Bahareh
Toorang, Fatemeh
Mohebbi, Elham
Zendehdel, Kazem
Azadbakht, Leila
author_facet Sasanfar, Bahareh
Toorang, Fatemeh
Mohebbi, Elham
Zendehdel, Kazem
Azadbakht, Leila
author_sort Sasanfar, Bahareh
collection PubMed
description BACKGROUND: A few studies have examined the relationship between carbohydrate quality index (CQI) and risk of breast cancer (BC) among women in Middle Eastern countries. We studied the associations between carbohydrate quality index and the risk of BC in overall and by menopausal status. METHODS: In this case-control study, dietary intake of 461 women with pathologically confirmed BC within the past year were examined. The same information were collected for 495 apparently healthy controls using a 168-item validated FFQ. Carbohydrate quality was determined by considering four criteria including: ratio of solid carbohydrates to total carbohydrates, dietary fiber intake, GI and the ratio of whole grains to total grains. RESULTS: Mean GI and GL of participants were totally 57.5 ± 7.2 and 245.7 ± 64.7, respectively. A trend toward significant association was seen between GI and odds of BC in the whole population; such that after stratifying analysis by menopausal status, premenopausal women in the highest quartile of GI were 1.85 times higher likely to have BC than those in the lowest quartile (95% CI: 1.12, 3.07, P = 0.01). We found that women with the greatest CQI had lower odds for BC, compared with those with the lowest CQI (0.63; 95% CI: 0.43–0.94, P = 0.03). This association was remained after stratifying analysis by menopausal status in premenopausal (0.55; 95% CI: 0.34–0.90, P = 0.04). CONCLUSION: We found that GI was directly and CQI inversely associated with odds of BC. In order to determine the effects of dietary carbohydrate quality prospective cohort studies are needed.
format Online
Article
Text
id pubmed-8620945
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-86209452021-11-29 Dietary carbohydrate quality and risk of breast cancer among women Sasanfar, Bahareh Toorang, Fatemeh Mohebbi, Elham Zendehdel, Kazem Azadbakht, Leila Nutr J Research BACKGROUND: A few studies have examined the relationship between carbohydrate quality index (CQI) and risk of breast cancer (BC) among women in Middle Eastern countries. We studied the associations between carbohydrate quality index and the risk of BC in overall and by menopausal status. METHODS: In this case-control study, dietary intake of 461 women with pathologically confirmed BC within the past year were examined. The same information were collected for 495 apparently healthy controls using a 168-item validated FFQ. Carbohydrate quality was determined by considering four criteria including: ratio of solid carbohydrates to total carbohydrates, dietary fiber intake, GI and the ratio of whole grains to total grains. RESULTS: Mean GI and GL of participants were totally 57.5 ± 7.2 and 245.7 ± 64.7, respectively. A trend toward significant association was seen between GI and odds of BC in the whole population; such that after stratifying analysis by menopausal status, premenopausal women in the highest quartile of GI were 1.85 times higher likely to have BC than those in the lowest quartile (95% CI: 1.12, 3.07, P = 0.01). We found that women with the greatest CQI had lower odds for BC, compared with those with the lowest CQI (0.63; 95% CI: 0.43–0.94, P = 0.03). This association was remained after stratifying analysis by menopausal status in premenopausal (0.55; 95% CI: 0.34–0.90, P = 0.04). CONCLUSION: We found that GI was directly and CQI inversely associated with odds of BC. In order to determine the effects of dietary carbohydrate quality prospective cohort studies are needed. BioMed Central 2021-11-26 /pmc/articles/PMC8620945/ /pubmed/34823559 http://dx.doi.org/10.1186/s12937-021-00752-y Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Sasanfar, Bahareh
Toorang, Fatemeh
Mohebbi, Elham
Zendehdel, Kazem
Azadbakht, Leila
Dietary carbohydrate quality and risk of breast cancer among women
title Dietary carbohydrate quality and risk of breast cancer among women
title_full Dietary carbohydrate quality and risk of breast cancer among women
title_fullStr Dietary carbohydrate quality and risk of breast cancer among women
title_full_unstemmed Dietary carbohydrate quality and risk of breast cancer among women
title_short Dietary carbohydrate quality and risk of breast cancer among women
title_sort dietary carbohydrate quality and risk of breast cancer among women
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8620945/
https://www.ncbi.nlm.nih.gov/pubmed/34823559
http://dx.doi.org/10.1186/s12937-021-00752-y
work_keys_str_mv AT sasanfarbahareh dietarycarbohydratequalityandriskofbreastcanceramongwomen
AT toorangfatemeh dietarycarbohydratequalityandriskofbreastcanceramongwomen
AT mohebbielham dietarycarbohydratequalityandriskofbreastcanceramongwomen
AT zendehdelkazem dietarycarbohydratequalityandriskofbreastcanceramongwomen
AT azadbakhtleila dietarycarbohydratequalityandriskofbreastcanceramongwomen