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First Detection and Genetic Characterization of New Equine Parvovirus Species Circulating among Horses in Korea

Equine parvovirus-cerebrospinal fluid (EqPV-CSF) and eqcopivirus (EqCoPV) are new parvovirus species (EqPVs) identified from various tissues (CSF, blood, and respiratory swabs) in horses with neurologic and respiratory diseases. In this study, we described the prevalence rate of EqPV-CSF and EqCoPV...

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Autores principales: Yoon, Jungho, Park, Taemook, Kim, Ahram, Song, Heeeun, Park, Byung-Joo, Ahn, Hee-Seop, Go, Hyeon-Jeong, Kim, Dong-Hwi, Lee, Joong-Bok, Park, Seung-Yong, Song, Chang-Seon, Lee, Sang-Won, Choi, In-Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621016/
https://www.ncbi.nlm.nih.gov/pubmed/34822641
http://dx.doi.org/10.3390/vetsci8110268
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author Yoon, Jungho
Park, Taemook
Kim, Ahram
Song, Heeeun
Park, Byung-Joo
Ahn, Hee-Seop
Go, Hyeon-Jeong
Kim, Dong-Hwi
Lee, Joong-Bok
Park, Seung-Yong
Song, Chang-Seon
Lee, Sang-Won
Choi, In-Soo
author_facet Yoon, Jungho
Park, Taemook
Kim, Ahram
Song, Heeeun
Park, Byung-Joo
Ahn, Hee-Seop
Go, Hyeon-Jeong
Kim, Dong-Hwi
Lee, Joong-Bok
Park, Seung-Yong
Song, Chang-Seon
Lee, Sang-Won
Choi, In-Soo
author_sort Yoon, Jungho
collection PubMed
description Equine parvovirus-cerebrospinal fluid (EqPV-CSF) and eqcopivirus (EqCoPV) are new parvovirus species (EqPVs) identified from various tissues (CSF, blood, and respiratory swabs) in horses with neurologic and respiratory diseases. In this study, we described the prevalence rate of EqPV-CSF and EqCoPV in 133 and 77 serum and fecal samples, respectively, using polymerase chain reaction. Further, we analyzed the potential risk factors for infection. We calculated the nucleotide and amino acid similarity and constructed phylogenetic trees. There was a moderate-to-high prevalence rate (EqPV-CSF: 3.8%; EqCoPV 9.8%) of each virus in serum; moreover, age, country of foaling, and clinical colic signs were significantly associated with the EqPVs infection. The newly identified EqPV-CSF/EqCoPV genomes had high nucleotide and amino acid identities with previously isolated strains in the USA. In phylogenetic analysis, they clustered and formed a new subgroup in the genus Copiparvovirus. To our knowledge, this is the first field epidemiologic study on EqPV-CSF and EqCoPV using both serum and fecal samples. Our findings demonstrate the risk factors for infection and could facilitate the development of disease prevention strategies.
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spelling pubmed-86210162021-11-27 First Detection and Genetic Characterization of New Equine Parvovirus Species Circulating among Horses in Korea Yoon, Jungho Park, Taemook Kim, Ahram Song, Heeeun Park, Byung-Joo Ahn, Hee-Seop Go, Hyeon-Jeong Kim, Dong-Hwi Lee, Joong-Bok Park, Seung-Yong Song, Chang-Seon Lee, Sang-Won Choi, In-Soo Vet Sci Article Equine parvovirus-cerebrospinal fluid (EqPV-CSF) and eqcopivirus (EqCoPV) are new parvovirus species (EqPVs) identified from various tissues (CSF, blood, and respiratory swabs) in horses with neurologic and respiratory diseases. In this study, we described the prevalence rate of EqPV-CSF and EqCoPV in 133 and 77 serum and fecal samples, respectively, using polymerase chain reaction. Further, we analyzed the potential risk factors for infection. We calculated the nucleotide and amino acid similarity and constructed phylogenetic trees. There was a moderate-to-high prevalence rate (EqPV-CSF: 3.8%; EqCoPV 9.8%) of each virus in serum; moreover, age, country of foaling, and clinical colic signs were significantly associated with the EqPVs infection. The newly identified EqPV-CSF/EqCoPV genomes had high nucleotide and amino acid identities with previously isolated strains in the USA. In phylogenetic analysis, they clustered and formed a new subgroup in the genus Copiparvovirus. To our knowledge, this is the first field epidemiologic study on EqPV-CSF and EqCoPV using both serum and fecal samples. Our findings demonstrate the risk factors for infection and could facilitate the development of disease prevention strategies. MDPI 2021-11-07 /pmc/articles/PMC8621016/ /pubmed/34822641 http://dx.doi.org/10.3390/vetsci8110268 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yoon, Jungho
Park, Taemook
Kim, Ahram
Song, Heeeun
Park, Byung-Joo
Ahn, Hee-Seop
Go, Hyeon-Jeong
Kim, Dong-Hwi
Lee, Joong-Bok
Park, Seung-Yong
Song, Chang-Seon
Lee, Sang-Won
Choi, In-Soo
First Detection and Genetic Characterization of New Equine Parvovirus Species Circulating among Horses in Korea
title First Detection and Genetic Characterization of New Equine Parvovirus Species Circulating among Horses in Korea
title_full First Detection and Genetic Characterization of New Equine Parvovirus Species Circulating among Horses in Korea
title_fullStr First Detection and Genetic Characterization of New Equine Parvovirus Species Circulating among Horses in Korea
title_full_unstemmed First Detection and Genetic Characterization of New Equine Parvovirus Species Circulating among Horses in Korea
title_short First Detection and Genetic Characterization of New Equine Parvovirus Species Circulating among Horses in Korea
title_sort first detection and genetic characterization of new equine parvovirus species circulating among horses in korea
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621016/
https://www.ncbi.nlm.nih.gov/pubmed/34822641
http://dx.doi.org/10.3390/vetsci8110268
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