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First Detection and Genetic Characterization of New Equine Parvovirus Species Circulating among Horses in Korea
Equine parvovirus-cerebrospinal fluid (EqPV-CSF) and eqcopivirus (EqCoPV) are new parvovirus species (EqPVs) identified from various tissues (CSF, blood, and respiratory swabs) in horses with neurologic and respiratory diseases. In this study, we described the prevalence rate of EqPV-CSF and EqCoPV...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621016/ https://www.ncbi.nlm.nih.gov/pubmed/34822641 http://dx.doi.org/10.3390/vetsci8110268 |
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author | Yoon, Jungho Park, Taemook Kim, Ahram Song, Heeeun Park, Byung-Joo Ahn, Hee-Seop Go, Hyeon-Jeong Kim, Dong-Hwi Lee, Joong-Bok Park, Seung-Yong Song, Chang-Seon Lee, Sang-Won Choi, In-Soo |
author_facet | Yoon, Jungho Park, Taemook Kim, Ahram Song, Heeeun Park, Byung-Joo Ahn, Hee-Seop Go, Hyeon-Jeong Kim, Dong-Hwi Lee, Joong-Bok Park, Seung-Yong Song, Chang-Seon Lee, Sang-Won Choi, In-Soo |
author_sort | Yoon, Jungho |
collection | PubMed |
description | Equine parvovirus-cerebrospinal fluid (EqPV-CSF) and eqcopivirus (EqCoPV) are new parvovirus species (EqPVs) identified from various tissues (CSF, blood, and respiratory swabs) in horses with neurologic and respiratory diseases. In this study, we described the prevalence rate of EqPV-CSF and EqCoPV in 133 and 77 serum and fecal samples, respectively, using polymerase chain reaction. Further, we analyzed the potential risk factors for infection. We calculated the nucleotide and amino acid similarity and constructed phylogenetic trees. There was a moderate-to-high prevalence rate (EqPV-CSF: 3.8%; EqCoPV 9.8%) of each virus in serum; moreover, age, country of foaling, and clinical colic signs were significantly associated with the EqPVs infection. The newly identified EqPV-CSF/EqCoPV genomes had high nucleotide and amino acid identities with previously isolated strains in the USA. In phylogenetic analysis, they clustered and formed a new subgroup in the genus Copiparvovirus. To our knowledge, this is the first field epidemiologic study on EqPV-CSF and EqCoPV using both serum and fecal samples. Our findings demonstrate the risk factors for infection and could facilitate the development of disease prevention strategies. |
format | Online Article Text |
id | pubmed-8621016 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86210162021-11-27 First Detection and Genetic Characterization of New Equine Parvovirus Species Circulating among Horses in Korea Yoon, Jungho Park, Taemook Kim, Ahram Song, Heeeun Park, Byung-Joo Ahn, Hee-Seop Go, Hyeon-Jeong Kim, Dong-Hwi Lee, Joong-Bok Park, Seung-Yong Song, Chang-Seon Lee, Sang-Won Choi, In-Soo Vet Sci Article Equine parvovirus-cerebrospinal fluid (EqPV-CSF) and eqcopivirus (EqCoPV) are new parvovirus species (EqPVs) identified from various tissues (CSF, blood, and respiratory swabs) in horses with neurologic and respiratory diseases. In this study, we described the prevalence rate of EqPV-CSF and EqCoPV in 133 and 77 serum and fecal samples, respectively, using polymerase chain reaction. Further, we analyzed the potential risk factors for infection. We calculated the nucleotide and amino acid similarity and constructed phylogenetic trees. There was a moderate-to-high prevalence rate (EqPV-CSF: 3.8%; EqCoPV 9.8%) of each virus in serum; moreover, age, country of foaling, and clinical colic signs were significantly associated with the EqPVs infection. The newly identified EqPV-CSF/EqCoPV genomes had high nucleotide and amino acid identities with previously isolated strains in the USA. In phylogenetic analysis, they clustered and formed a new subgroup in the genus Copiparvovirus. To our knowledge, this is the first field epidemiologic study on EqPV-CSF and EqCoPV using both serum and fecal samples. Our findings demonstrate the risk factors for infection and could facilitate the development of disease prevention strategies. MDPI 2021-11-07 /pmc/articles/PMC8621016/ /pubmed/34822641 http://dx.doi.org/10.3390/vetsci8110268 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Yoon, Jungho Park, Taemook Kim, Ahram Song, Heeeun Park, Byung-Joo Ahn, Hee-Seop Go, Hyeon-Jeong Kim, Dong-Hwi Lee, Joong-Bok Park, Seung-Yong Song, Chang-Seon Lee, Sang-Won Choi, In-Soo First Detection and Genetic Characterization of New Equine Parvovirus Species Circulating among Horses in Korea |
title | First Detection and Genetic Characterization of New Equine Parvovirus Species Circulating among Horses in Korea |
title_full | First Detection and Genetic Characterization of New Equine Parvovirus Species Circulating among Horses in Korea |
title_fullStr | First Detection and Genetic Characterization of New Equine Parvovirus Species Circulating among Horses in Korea |
title_full_unstemmed | First Detection and Genetic Characterization of New Equine Parvovirus Species Circulating among Horses in Korea |
title_short | First Detection and Genetic Characterization of New Equine Parvovirus Species Circulating among Horses in Korea |
title_sort | first detection and genetic characterization of new equine parvovirus species circulating among horses in korea |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621016/ https://www.ncbi.nlm.nih.gov/pubmed/34822641 http://dx.doi.org/10.3390/vetsci8110268 |
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