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Overview of Metabolomic Analysis and the Integration with Multi-Omics for Economic Traits in Cattle

Metabolomics has been applied to measure the dynamic metabolic responses, to understand the systematic biological networks, to reveal the potential genetic architecture, etc., for human diseases and livestock traits. For example, the current published results include the detected relevant candidate...

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Detalles Bibliográficos
Autores principales: Hao, Dan, Bai, Jiangsong, Du, Jianyong, Wu, Xiaoping, Thomsen, Bo, Gao, Hongding, Su, Guosheng, Wang, Xiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621036/
https://www.ncbi.nlm.nih.gov/pubmed/34822411
http://dx.doi.org/10.3390/metabo11110753
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author Hao, Dan
Bai, Jiangsong
Du, Jianyong
Wu, Xiaoping
Thomsen, Bo
Gao, Hongding
Su, Guosheng
Wang, Xiao
author_facet Hao, Dan
Bai, Jiangsong
Du, Jianyong
Wu, Xiaoping
Thomsen, Bo
Gao, Hongding
Su, Guosheng
Wang, Xiao
author_sort Hao, Dan
collection PubMed
description Metabolomics has been applied to measure the dynamic metabolic responses, to understand the systematic biological networks, to reveal the potential genetic architecture, etc., for human diseases and livestock traits. For example, the current published results include the detected relevant candidate metabolites, identified metabolic pathways, potential systematic networks, etc., for different cattle traits that can be applied for further metabolomic and integrated omics studies. Therefore, summarizing the applications of metabolomics for economic traits is required in cattle. We here provide a comprehensive review about metabolomic analysis and its integration with other omics in five aspects: (1) characterization of the metabolomic profile of cattle; (2) metabolomic applications in cattle; (3) integrated metabolomic analysis with other omics; (4) methods and tools in metabolomic analysis; and (5) further potentialities. The review aims to investigate the existing metabolomic studies by highlighting the results in cattle, integrated with other omics studies, to understand the metabolic mechanisms underlying the economic traits and to provide useful information for further research and practical breeding programs in cattle.
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spelling pubmed-86210362021-11-27 Overview of Metabolomic Analysis and the Integration with Multi-Omics for Economic Traits in Cattle Hao, Dan Bai, Jiangsong Du, Jianyong Wu, Xiaoping Thomsen, Bo Gao, Hongding Su, Guosheng Wang, Xiao Metabolites Review Metabolomics has been applied to measure the dynamic metabolic responses, to understand the systematic biological networks, to reveal the potential genetic architecture, etc., for human diseases and livestock traits. For example, the current published results include the detected relevant candidate metabolites, identified metabolic pathways, potential systematic networks, etc., for different cattle traits that can be applied for further metabolomic and integrated omics studies. Therefore, summarizing the applications of metabolomics for economic traits is required in cattle. We here provide a comprehensive review about metabolomic analysis and its integration with other omics in five aspects: (1) characterization of the metabolomic profile of cattle; (2) metabolomic applications in cattle; (3) integrated metabolomic analysis with other omics; (4) methods and tools in metabolomic analysis; and (5) further potentialities. The review aims to investigate the existing metabolomic studies by highlighting the results in cattle, integrated with other omics studies, to understand the metabolic mechanisms underlying the economic traits and to provide useful information for further research and practical breeding programs in cattle. MDPI 2021-10-30 /pmc/articles/PMC8621036/ /pubmed/34822411 http://dx.doi.org/10.3390/metabo11110753 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Hao, Dan
Bai, Jiangsong
Du, Jianyong
Wu, Xiaoping
Thomsen, Bo
Gao, Hongding
Su, Guosheng
Wang, Xiao
Overview of Metabolomic Analysis and the Integration with Multi-Omics for Economic Traits in Cattle
title Overview of Metabolomic Analysis and the Integration with Multi-Omics for Economic Traits in Cattle
title_full Overview of Metabolomic Analysis and the Integration with Multi-Omics for Economic Traits in Cattle
title_fullStr Overview of Metabolomic Analysis and the Integration with Multi-Omics for Economic Traits in Cattle
title_full_unstemmed Overview of Metabolomic Analysis and the Integration with Multi-Omics for Economic Traits in Cattle
title_short Overview of Metabolomic Analysis and the Integration with Multi-Omics for Economic Traits in Cattle
title_sort overview of metabolomic analysis and the integration with multi-omics for economic traits in cattle
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621036/
https://www.ncbi.nlm.nih.gov/pubmed/34822411
http://dx.doi.org/10.3390/metabo11110753
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