Novel Triterpenoids from Cassia fistula Stem Bark Depreciates STZ-Induced Detrimental Changes in IRS-1/Akt-Mediated Insulin Signaling Mechanisms in Type-1 Diabetic Rats

Here, we identified the mechanisms of action of antidiabetic activity of novel compounds isolated from Cassia fistula stem bark in STZ-diabetic animals. Novel triterpenoid compounds (C1, C2 and C3) were treated to STZ-administered diabetic animals at a concentration of 20mg/kg body weight orally for...

Descripción completa

Detalles Bibliográficos
Autores principales: Indu, Sabapathy, Vijayalakshmi, Periyasamy, Selvaraj, Jayaraman, Rajalakshmi, Manikkam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621110/
https://www.ncbi.nlm.nih.gov/pubmed/34833905
http://dx.doi.org/10.3390/molecules26226812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621110/
https://www.ncbi.nlm.nih.gov/pubmed/34833905
http://dx.doi.org/10.3390/molecules26226812

Ejemplares similares