Cargando…

Therapeutic Potential of Ursolic Acid in Cancer and Diabetic Neuropathy Diseases

Ursolic acid (UA) is a pentacyclic triterpenoid frequently found in medicinal herbs and plants, having numerous pharmacological effects. UA and its analogs treat multiple diseases, including cancer, diabetic neuropathy, and inflammatory diseases. UA inhibits cancer proliferation, metastasis, angioge...

Descripción completa

Detalles Bibliográficos
Autores principales:	Alam, Manzar, Ali, Sabeeha, Ahmed, Sarfraz, Elasbali, Abdelbaset Mohamed, Adnan, Mohd, Islam, Asimul, Hassan, Md. Imtaiyaz, Yadav, Dharmendra Kumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621142/ https://www.ncbi.nlm.nih.gov/pubmed/34830043 http://dx.doi.org/10.3390/ijms222212162

Ejemplares similares

Therapeutic Implications of Caffeic Acid in Cancer and Neurological Diseases
por: Alam, Manzar, et al.
Publicado: (2022)

Natural products can be used in therapeutic management of COVID-19: Probable mechanistic insights
por: Ali, Sabeeha, et al.
Publicado: (2022)

Effect of pH on the structure and function of cyclin-dependent kinase 6
por: Yousuf, Mohd, et al.
Publicado: (2022)

B Cell Lymphoma 2: A Potential Therapeutic Target for Cancer Therapy
por: Alam, Manzar, et al.
Publicado: (2021)

Insights into the Antibacterial Activity of Prolactin-Inducible Protein against the Standard and Environmental MDR Bacterial Strains
por: Yousuf, Mohd, et al.
Publicado: (2022)

Potential Therapeutic Implications of Caffeic Acid in Cancer Signaling: Past, Present, and Future
por: Alam, Manzar, et al.
Publicado: (2022)

Delineating the Aggregation-Prone Hotspot Regions (Peptides) in the Human Cu/Zn Superoxide Dismutase 1
por: Wahiduzzaman,, et al.
Publicado: (2021)

Inhibiting Cyclin-Dependent Kinase 6 by Taurine: Implications in Anticancer Therapeutics
por: Yousuf, Mohd, et al.
Publicado: (2022)

Bax/Bcl-2 Cascade Is Regulated by the EGFR Pathway: Therapeutic Targeting of Non-Small Cell Lung Cancer
por: Alam, Manzar, et al.
Publicado: (2022)

Discovering Tuberosin and Villosol as Potent and Selective Inhibitors of AKT1 for Therapeutic Targeting of Oral Squamous Cell Carcinoma
por: Adnan, Mohd, et al.
Publicado: (2022)

Investigating host-virus interaction mechanism and phylogenetic analysis of viral proteins involved in the pathogenesis
por: Naqvi, Ahmad Abu Turab, et al.
Publicado: (2021)

Investigating single amino acid substitutions in PIM1 kinase: A structural genomics approach
por: Shafie, Alaa, et al.
Publicado: (2021)

Pharmacological attributes of Bacopa monnieri extract: Current updates and clinical manifestation
por: Fatima, Urooj, et al.
Publicado: (2022)

MAP/Microtubule Affinity Regulating Kinase 4 Inhibitory Potential of Irisin: A New Therapeutic Strategy to Combat Cancer and Alzheimer’s Disease
por: Waseem, Rashid, et al.
Publicado: (2021)

Structure-Guided Approach to Discover Tuberosin as a Potent Activator of Pyruvate Kinase M2, Targeting Cancer Therapy
por: Adnan, Mohd, et al.
Publicado: (2022)

Impact of Single Amino Acid Substitutions in Parkinsonism-Associated Deglycase-PARK7 and Their Association with Parkinson’s Disease
por: Anjum, Farah, et al.
Publicado: (2022)

Cooperative Unfolding of Residual Structure in Heat Denatured Proteins by Urea and Guanidinium Chloride
por: Singh, Ritu, et al.
Publicado: (2015)

Purification and characterization of RGA2, a Rho2 GTPase-activating protein from Tinospora cordifolia
por: Amir, Mohd., et al.
Publicado: (2016)

Therapeutic Targeting of Regulated Signaling Pathways of Non-Small Cell Lung Carcinoma
por: Hasan, Gulam Mustafa, et al.
Publicado: (2023)

Biomedical features and therapeutic potential of rosmarinic acid
por: Noor, Saba, et al.
Publicado: (2022)

Potential drug targets of SARS-CoV-2: From genomics to therapeutics
por: Shamsi, Anas, et al.
Publicado: (2021)

Evaluation of Binding of Rosmarinic Acid with Human Transferrin and Its Impact on the Protein Structure: Targeting Polyphenolic Acid-Induced Protection of Neurodegenerative Disorders
por: Shamsi, Anas, et al.
Publicado: (2020)

Ellagic Acid Controls Cell Proliferation and Induces Apoptosis in Breast Cancer Cells via Inhibition of Cyclin-Dependent Kinase 6
por: Yousuf, Mohd, et al.
Publicado: (2020)

Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases
por: Azhar, Md. Khabeer, et al.
Publicado: (2023)

Ursolic Acid Analogs as Potential Therapeutics for Cancer
por: Panda, Siva S., et al.
Publicado: (2022)

Therapeutic Potential of Ursonic Acid: Comparison with Ursolic Acid
por: Son, Juhyeon, et al.
Publicado: (2020)

Editorial: Molecular dynamics of cognitive-motor impairment in neurodegenerative diseases
por: Kumar, Dhiraj, et al.
Publicado: (2023)

Heterogeneity of Equilibrium Molten Globule State of Cytochrome c Induced by Weak Salt Denaturants under Physiological Condition
por: Rahaman, Hamidur, et al.
Publicado: (2015)

Carbohydrate-Based Macromolecular Crowding-Induced Stabilization of Proteins: Towards Understanding the Significance of the Size of the Crowder
por: Shahid, Sumra, et al.
Publicado: (2019)

Targeting the Sphingosine Kinase/Sphingosine-1-Phosphate Signaling Axis in Drug Discovery for Cancer Therapy
por: Gupta, Preeti, et al.
Publicado: (2021)

Rosmarinic Acid Exhibits Anticancer Effects via MARK4 Inhibition
por: Anwar, Saleha, et al.
Publicado: (2020)

Comparative analysis of web-based programs for single amino acid substitutions in proteins
por: Choudhury, Arunabh, et al.
Publicado: (2022)

Topical Insights Into the Post-Approval Controversies of Aducanumab
por: Kumar, Dhiraj, et al.
Publicado: (2021)

Data on the role of accessible surface area on osmolytes-induced protein stabilization
por: Rahman, Safikur, et al.
Publicado: (2016)

Effects of Ethylene Glycol on the Structure and Stability of Myoglobin Using Spectroscopic, Interaction, and In Silico Approaches: Monomer Is Different from Those of Its Polymers
por: Parray, Zahoor Ahmad, et al.
Publicado: (2020)

Interaction of polyethylene glycol with cytochrome c investigated via in vitro and in silico approaches
por: Parray, Zahoor Ahmad, et al.
Publicado: (2021)

Therapeutic effect of ursolic acid in experimental visceral leishmaniasis
por: Jesus, Jéssica A., et al.
Publicado: (2016)

A Network-Guided Approach to Discover Phytochemical-Based Anticancer Therapy: Targeting MARK4 for Hepatocellular Carcinoma
por: Ahmed, Sarfraz, et al.
Publicado: (2022)

Structural Features of Nucleoprotein CST/Shelterin Complex Involved in the Telomere Maintenance and Its Association with Disease Mutations
por: Amir, Mohd., et al.
Publicado: (2020)

Bioactive Phytoconstituents as Potent Inhibitors of Tyrosine-Protein Kinase Yes (YES1): Implications in Anticancer Therapeutics
por: Yang, Chunmin, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rh5q350qr3kaq1qvfrjr1jojhu