Cargando…

Nifuroxazide Mitigates Angiogenesis in Ehlrich’s Solid Carcinoma: Molecular Docking, Bioinformatic and Experimental Studies on Inhibition of Il-6/Jak2/Stat3 Signaling

Nifuroxazide is an antidiarrheal medication that has promising anticancer activity against diverse types of tumors. The present study tested the anticancer activity of nifuroxazide against Ehrlich’s mammary carcinoma grown in vivo. Furthermore, we investigated the effect of nifuroxazide on IL-6/jak2...

Descripción completa

Detalles Bibliográficos
Autores principales:	El-Sherbiny, Mohamed, El-Sayed, Rehab M., Helal, Mohamed A., Ibrahiem, Afaf T., Elmahdi, Hoda S., Eladl, Mohamed Ahmed, Bilay, Shymaa E., Alshahrani, Asma M., Tawfik, Mona K., Hamed, Ziad E., Mohamed, Amany O., Zaitone, Sawsan A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621155/ https://www.ncbi.nlm.nih.gov/pubmed/34833950 http://dx.doi.org/10.3390/molecules26226858

Ejemplares similares

Formulation and Characterization of Doxycycline-Loaded Polymeric Nanoparticles for Testing Antitumor/Antiangiogenic Action in Experimental Colon Cancer in Mice
por: Alshaman, Reem, et al.
Publicado: (2022)

Leflunomide Induces Dose-Dependent Lung Injury in Mice via Stimulating Vimentin and NLRP3 Inflammasome Production
por: El-Sherbiny, Mohamed, et al.
Publicado: (2021)

Ultrastructural changes and nestin expression accompanying compensatory renal growth after unilateral nephrectomy in adult rats
por: Eladl, Mohamed Ahmed, et al.
Publicado: (2017)

Metformin Protects From Rotenone–Induced Nigrostriatal Neuronal Death in Adult Mice by Activating AMPK-FOXO3 Signaling and Mitigation of Angiogenesis
por: El-Ghaiesh, Sabah H., et al.
Publicado: (2020)

Electrochemical stripping voltammetrical sensor based on polypyrrole exfoliated polyetheramine–montmorillonite nanocomposite for nanomolar detection of nifuroxazide
por: Elfiky, Mona, et al.
Publicado: (2023)

Formulation and Characterization of Metformin-Loaded Ethosomes for Topical Application to Experimentally Induced Skin Cancer in Mice
por: Mousa, Ibrahim A., et al.
Publicado: (2022)

Novel Mechanism for Memantine in Attenuating Diabetic Neuropathic Pain in Mice via Downregulating the Spinal HMGB1/TRL4/NF-kB Inflammatory Axis
por: Alomar, Suliman Y., et al.
Publicado: (2021)

Sexual Dimorphism Impact on the Ground Reaction Force Acting on the Mediolateral Direction During Level Walking: Hip Abductor Muscle Biomechanics and Its Correlation to GRF Moment Arm
por: Abd-Eltawab, Amany E., et al.
Publicado: (2022)

Supplement With Calcium or Alendronate Suppresses Osteopenia Due to Long Term Rabeprazole Treatment in Female Mice: Influence on Bone TRAP and Osteopontin Levels
por: Shaalan, Aly A.M., et al.
Publicado: (2020)

Carbamazepine Alleviates Retinal and Optic Nerve Neural Degeneration in Diabetic Mice via Nerve Growth Factor-Induced PI3K/Akt/mTOR Activation
por: Elsherbiny, Nehal M., et al.
Publicado: (2019)

α-Hederin Saponin Augments the Chemopreventive Effect of Cisplatin against Ehrlich Tumors and Bioinformatic Approach Identifying the Role of SDF1/CXCR4/p-AKT-1/NFκB Signaling
por: Elaidy, Samah M., et al.
Publicado: (2023)

Protective effect of nano vitamin D against fatty degeneration in submandibular and sublingual salivary glands: A histological and ultrastructural study
por: Al-Serwi, Rasha Hamed, et al.
Publicado: (2021)

Prognostic Role of Tumor Microenvironment in DLBCL and Relation to Patients' Clinical Outcome: A Clinical and Immunohistochemical Study
por: Ghorab, Doaa Shams-Deen, et al.
Publicado: (2022)

Evaluation of miRNA-196a2 and apoptosis-related target genes: ANXA1, DFFA and PDCD4 expression in gastrointestinal cancer patients: A pilot study
por: Fawzy, Manal S., et al.
Publicado: (2017)

Raspberry Ketones Attenuate Cyclophosphamide-Induced Pulmonary Toxicity in Mice through Inhibition of Oxidative Stress and NF-ΚB Pathway
por: Mohamed, Marwa T., et al.
Publicado: (2020)

Immunohistochemical Expression of Stanniocalcin 2 in Colorectal Cancer: A Retrospective Egyptian Study
por: El hanbuli, Hala M., et al.
Publicado: (2022)

Whole-Body Vibration Impacts on the Degree of Toe Angle and Its Correlation to the Knee Osteoarthritis Index during Level Walking among Female University Students: A Randomized Controlled Trial
por: Abd-Eltawab, Amany E., et al.
Publicado: (2023)

A validated spectrofluorimetric method for the determination of nifuroxazide through coumarin formation using experimental design
por: El-Zaher, Asmaa Ahmed, et al.
Publicado: (2013)

Targeted Drug Administration onto Cancer Cells Using Hyaluronic Acid–Quercetin-Conjugated Silver Nanoparticles
por: Al-Serwi, Rasha H., et al.
Publicado: (2023)

Implications of Three-Dimensional Cell Culture in Cancer Therapeutic Research
por: Poornima, Kolluri, et al.
Publicado: (2022)

Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanoma
por: Zhu, Yongxia, et al.
Publicado: (2016)

Nifuroxazide induces apoptosis and impairs pulmonary metastasis in breast cancer model
por: Yang, F, et al.
Publicado: (2015)

Disorders of sexual differentiation: I. Genetics and pathology
por: El-Sherbiny, Mohamed
Publicado: (2013)

Disorders of sexual differentiation: II. Diagnosis and treatment
por: El-Sherbiny, Mohamed
Publicado: (2013)

Increased Expression and Activity of 12-Lipoxygenase in Oxygen-Induced Ischemic Retinopathy and Proliferative Diabetic Retinopathy: Implications in Retinal Neovascularization
por: Al-Shabrawey, Mohamed, et al.
Publicado: (2011)

Vitamin K2 (Menaquinone-7) Reverses Age-Related Structural and Cognitive Deterioration in Naturally Aging Rats
por: Elkattawy, Hany A., et al.
Publicado: (2022)

An Ideal Approach for Enhancing 5-Fluorouracil Anticancer Efficacy by Nanoemulsion for Cytotoxicity against a Human Hepatoma Cell Line (HepG2 Cells)
por: Mohamed, Jamal Moideen Muthu, et al.
Publicado: (2022)

Curcumin Modulates Oxidative Stress, Fibrosis, and Apoptosis in Drug-Resistant Cancer Cell Lines
por: Gabr, Sami A., et al.
Publicado: (2022)

Prognostic Value of BRAF, Programmed Cell Death 1 (PD1), and PD Ligand 1 (PDL1) Protein Expression in Colon Adenocarcinoma
por: Ibrahiem, Afaf T., et al.
Publicado: (2023)

Indapamide Increases IRS1 Expression and Modifies Adiponectin/NLRP3/PPARγ Crosstalk in Type 2 Diabetic Rats
por: Samaha, Mahmoud M., et al.
Publicado: (2022)

Open Clinical Trial on Using Nifuroxazide Compared to Probiotics in Treating Acute Diarrhoeas in Adults
por: Begovic, Begler, et al.
Publicado: (2016)

ALDH1 Bio-activates Nifuroxazide to Eradicate ALDH(High) Melanoma-Initiating Cells
por: Sarvi, Sana, et al.
Publicado: (2018)

Nifuroxazide ameliorates pulmonary fibrosis by blocking myofibroblast genesis: a drug repurposing study
por: Gan, Cailing, et al.
Publicado: (2022)

Nifuroxazide ameliorates lipid and glucose metabolism in palmitate-induced HepG2 cells
por: Liu, Jing-Yi, et al.
Publicado: (2019)

Author Correction: Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanoma
por: Zhu, Yongxia, et al.
Publicado: (2022)

Nifuroxazide Activates the Parthanatos to Overcome TMPRSS2:ERG Fusion-Positive Prostate Cancer
por: Li, Chengxun, et al.
Publicado: (2023)

The Existing Drug Nifuroxazide as an Antischistosomal Agent: In Vitro, In Vivo, and In Silico Studies of Macromolecular Targets
por: Roquini, Vinícius, et al.
Publicado: (2023)

The JAK inhibitor ruxolitinib abrogates immune hepatitis instigated by concanavalin A in mice
por: Shaker, Mohamed E., et al.
Publicado: (2022)

Peeling Skin Syndrome: A Pathologically Invisible Dermatosis
por: El Hanbuli, Hala M., et al.
Publicado: (2019)

Epidermolytic Hyperkeratosis: A Challenging Pathology for Clinical Correlation
por: El Hanbuli, Hala M., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_cl9o75742tonmhs59c32d4p5k1