New Uncharged 2-Thienostilbene Oximes as Reactivators of Organophosphate-Inhibited Cholinesterases

The inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) by organophosphates (OPs) as nerve agents and pesticides compromises normal cholinergic nerve signal transduction in the peripheral and central nervous systems (CNS) leading to cholinergic crisis. The treatment comprises...

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Detalles Bibliográficos
Autores principales: Mlakić, Milena, Čadež, Tena, Barić, Danijela, Puček, Ivana, Ratković, Ana, Marinić, Željko, Lasić, Kornelija, Kovarik, Zrinka, Škorić, Irena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621217/
https://www.ncbi.nlm.nih.gov/pubmed/34832929
http://dx.doi.org/10.3390/ph14111147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621217/
https://www.ncbi.nlm.nih.gov/pubmed/34832929
http://dx.doi.org/10.3390/ph14111147

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