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New Uncharged 2-Thienostilbene Oximes as Reactivators of Organophosphate-Inhibited Cholinesterases
The inhibition of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) by organophosphates (OPs) as nerve agents and pesticides compromises normal cholinergic nerve signal transduction in the peripheral and central nervous systems (CNS) leading to cholinergic crisis. The treatment comprises...
Autores principales: | Mlakić, Milena, Čadež, Tena, Barić, Danijela, Puček, Ivana, Ratković, Ana, Marinić, Željko, Lasić, Kornelija, Kovarik, Zrinka, Škorić, Irena |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621217/ https://www.ncbi.nlm.nih.gov/pubmed/34832929 http://dx.doi.org/10.3390/ph14111147 |
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