Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids May Extend above and below Pons and Is Associated with Other Autoimmune Diseases

Many autoimmune diseases can affect the central nervous system, and their varying clinical presentations often confound a straightforward diagnosis. In this report, we describe a unique presentation of CLIPPERS syndrome. To our knowledge, this is the first case to demonstrate significant supratentor...

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Autores principales: Berry, Brent, Joppa, Stephanie, Labin, Edward, Puram, Vikram, McCleary, Kaci, Clark, H. Brent, Nelson, Flavia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621219/
https://www.ncbi.nlm.nih.gov/pubmed/34832996
http://dx.doi.org/10.3390/life11111120
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author Berry, Brent
Joppa, Stephanie
Labin, Edward
Puram, Vikram
McCleary, Kaci
Clark, H. Brent
Nelson, Flavia
author_facet Berry, Brent
Joppa, Stephanie
Labin, Edward
Puram, Vikram
McCleary, Kaci
Clark, H. Brent
Nelson, Flavia
author_sort Berry, Brent
collection PubMed
description Many autoimmune diseases can affect the central nervous system, and their varying clinical presentations often confound a straightforward diagnosis. In this report, we describe a unique presentation of CLIPPERS syndrome. To our knowledge, this is the first case to demonstrate significant supratentorial involvement with symmetric and non-confluent lesions in the medial orbitofrontal cortex; additionally, this is the second case to describe an association between diagnoses of hypothyroidism and CLIPPERS.
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spelling pubmed-86212192021-11-27 Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids May Extend above and below Pons and Is Associated with Other Autoimmune Diseases Berry, Brent Joppa, Stephanie Labin, Edward Puram, Vikram McCleary, Kaci Clark, H. Brent Nelson, Flavia Life (Basel) Case Report Many autoimmune diseases can affect the central nervous system, and their varying clinical presentations often confound a straightforward diagnosis. In this report, we describe a unique presentation of CLIPPERS syndrome. To our knowledge, this is the first case to demonstrate significant supratentorial involvement with symmetric and non-confluent lesions in the medial orbitofrontal cortex; additionally, this is the second case to describe an association between diagnoses of hypothyroidism and CLIPPERS. MDPI 2021-10-21 /pmc/articles/PMC8621219/ /pubmed/34832996 http://dx.doi.org/10.3390/life11111120 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Berry, Brent
Joppa, Stephanie
Labin, Edward
Puram, Vikram
McCleary, Kaci
Clark, H. Brent
Nelson, Flavia
Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids May Extend above and below Pons and Is Associated with Other Autoimmune Diseases
title Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids May Extend above and below Pons and Is Associated with Other Autoimmune Diseases
title_full Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids May Extend above and below Pons and Is Associated with Other Autoimmune Diseases
title_fullStr Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids May Extend above and below Pons and Is Associated with Other Autoimmune Diseases
title_full_unstemmed Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids May Extend above and below Pons and Is Associated with Other Autoimmune Diseases
title_short Chronic Lymphocytic Inflammation with Pontine Perivascular Enhancement Responsive to Steroids May Extend above and below Pons and Is Associated with Other Autoimmune Diseases
title_sort chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids may extend above and below pons and is associated with other autoimmune diseases
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621219/
https://www.ncbi.nlm.nih.gov/pubmed/34832996
http://dx.doi.org/10.3390/life11111120
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