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A Case of Disseminated Herpes Zoster Presenting as Vesicles Limited to Skin Lesions with Lymphoma Cutis Involvement

After primary infection, varicella zoster virus (VZV) causes prolonged latent infections that may reactivate, depending on the immunologic status of the host. We present a case of VZV reactivation in a 10-year-old male patient that underwent unrelated peripheral blood stem cell transplantation (uPBS...

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Autores principales: Lee, Joo Yup, Kang, Hyun Mi, Kim, Seong Koo, Lee, Jae Wook, Chung, Nack-Gyun, Jeong, Dae Chul, Cho, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621271/
https://www.ncbi.nlm.nih.gov/pubmed/34828689
http://dx.doi.org/10.3390/children8110976
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author Lee, Joo Yup
Kang, Hyun Mi
Kim, Seong Koo
Lee, Jae Wook
Chung, Nack-Gyun
Jeong, Dae Chul
Cho, Bin
author_facet Lee, Joo Yup
Kang, Hyun Mi
Kim, Seong Koo
Lee, Jae Wook
Chung, Nack-Gyun
Jeong, Dae Chul
Cho, Bin
author_sort Lee, Joo Yup
collection PubMed
description After primary infection, varicella zoster virus (VZV) causes prolonged latent infections that may reactivate, depending on the immunologic status of the host. We present a case of VZV reactivation in a 10-year-old male patient that underwent unrelated peripheral blood stem cell transplantation (uPBSCT) for T-lymphoblastic lymphoma with lymphoma cutis lesions. This patient had a history of herpes zoster involving the right L2-5 dermatome and trigeminal V1 dermatome prior to uPBSCT. Three months post-uPBSCT, the patient’s underlying disease relapsed, and the patient presented with lymphoma cutis lesions. A few days after a skin biopsy was performed to pathologically confirm skin relapse, vesicles appeared only involving the skin areas with lymphoma cutis. This case illustrates how decreased areas of epidermal immune mechanisms may cause atypical presentations of varicella infection.
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spelling pubmed-86212712021-11-27 A Case of Disseminated Herpes Zoster Presenting as Vesicles Limited to Skin Lesions with Lymphoma Cutis Involvement Lee, Joo Yup Kang, Hyun Mi Kim, Seong Koo Lee, Jae Wook Chung, Nack-Gyun Jeong, Dae Chul Cho, Bin Children (Basel) Case Report After primary infection, varicella zoster virus (VZV) causes prolonged latent infections that may reactivate, depending on the immunologic status of the host. We present a case of VZV reactivation in a 10-year-old male patient that underwent unrelated peripheral blood stem cell transplantation (uPBSCT) for T-lymphoblastic lymphoma with lymphoma cutis lesions. This patient had a history of herpes zoster involving the right L2-5 dermatome and trigeminal V1 dermatome prior to uPBSCT. Three months post-uPBSCT, the patient’s underlying disease relapsed, and the patient presented with lymphoma cutis lesions. A few days after a skin biopsy was performed to pathologically confirm skin relapse, vesicles appeared only involving the skin areas with lymphoma cutis. This case illustrates how decreased areas of epidermal immune mechanisms may cause atypical presentations of varicella infection. MDPI 2021-10-28 /pmc/articles/PMC8621271/ /pubmed/34828689 http://dx.doi.org/10.3390/children8110976 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Lee, Joo Yup
Kang, Hyun Mi
Kim, Seong Koo
Lee, Jae Wook
Chung, Nack-Gyun
Jeong, Dae Chul
Cho, Bin
A Case of Disseminated Herpes Zoster Presenting as Vesicles Limited to Skin Lesions with Lymphoma Cutis Involvement
title A Case of Disseminated Herpes Zoster Presenting as Vesicles Limited to Skin Lesions with Lymphoma Cutis Involvement
title_full A Case of Disseminated Herpes Zoster Presenting as Vesicles Limited to Skin Lesions with Lymphoma Cutis Involvement
title_fullStr A Case of Disseminated Herpes Zoster Presenting as Vesicles Limited to Skin Lesions with Lymphoma Cutis Involvement
title_full_unstemmed A Case of Disseminated Herpes Zoster Presenting as Vesicles Limited to Skin Lesions with Lymphoma Cutis Involvement
title_short A Case of Disseminated Herpes Zoster Presenting as Vesicles Limited to Skin Lesions with Lymphoma Cutis Involvement
title_sort case of disseminated herpes zoster presenting as vesicles limited to skin lesions with lymphoma cutis involvement
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621271/
https://www.ncbi.nlm.nih.gov/pubmed/34828689
http://dx.doi.org/10.3390/children8110976
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