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A Novel Endoscopic Ultrasonography Imaging Technique for Depicting Microcirculation in Pancreatobiliary Lesions without the Need for Contrast-Enhancement: A Prospective Exploratory Study

Detective flow imaging endoscopic ultrasonography (DFI-EUS) provides a new method to image and detect fine vessels and low-velocity blood flow without using ultrasound contrast agents. The aim of this study was to evaluate the utility of DFI-EUS for pancreatobiliary lesions and lymph nodes. Between...

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Autores principales: Yamashita, Yasunobu, Yoshikawa, Takanori, Yamazaki, Hirofumi, Kawaji, Yuki, Tamura, Takashi, Hatamaru, Keiichi, Itonaga, Masahiro, Ashida, Reiko, Ida, Yoshiyuki, Maekita, Takao, Iguchi, Mikitaka, Kitano, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621279/
https://www.ncbi.nlm.nih.gov/pubmed/34829364
http://dx.doi.org/10.3390/diagnostics11112018
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author Yamashita, Yasunobu
Yoshikawa, Takanori
Yamazaki, Hirofumi
Kawaji, Yuki
Tamura, Takashi
Hatamaru, Keiichi
Itonaga, Masahiro
Ashida, Reiko
Ida, Yoshiyuki
Maekita, Takao
Iguchi, Mikitaka
Kitano, Masayuki
author_facet Yamashita, Yasunobu
Yoshikawa, Takanori
Yamazaki, Hirofumi
Kawaji, Yuki
Tamura, Takashi
Hatamaru, Keiichi
Itonaga, Masahiro
Ashida, Reiko
Ida, Yoshiyuki
Maekita, Takao
Iguchi, Mikitaka
Kitano, Masayuki
author_sort Yamashita, Yasunobu
collection PubMed
description Detective flow imaging endoscopic ultrasonography (DFI-EUS) provides a new method to image and detect fine vessels and low-velocity blood flow without using ultrasound contrast agents. The aim of this study was to evaluate the utility of DFI-EUS for pancreatobiliary lesions and lymph nodes. Between January 2019 and January 2020, 53 patients who underwent DFI-EUS, e-FLOW EUS, and contrast-enhanced EUS were enrolled. The ability of DFI-EUS and e-FLOW EUS to detect vessels was compared with that of contrast-enhanced EUS. This article describes the DFI technique along with our first experience of its use for vascular assessment of pancreatobiliary lesions. Vessels were imaged in 34 pancreatic solid lesions, eight intraductal papillary mucinous neoplasms (IPMNs), seven gall bladder lesions, and four swollen lymph nodes. DFI-EUS (91%) was significantly superior to e-FLOW EUS (53%) with respect to detection of vessels (p < 0.001) and for discrimination of mural nodules from mucous clots in IPMN and gallbladder lesions from sludge (p = 0.046). Thus, DFI-EUS has the potential to become an essential tool for diagnosis and vascular assessment of various diseases.
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spelling pubmed-86212792021-11-27 A Novel Endoscopic Ultrasonography Imaging Technique for Depicting Microcirculation in Pancreatobiliary Lesions without the Need for Contrast-Enhancement: A Prospective Exploratory Study Yamashita, Yasunobu Yoshikawa, Takanori Yamazaki, Hirofumi Kawaji, Yuki Tamura, Takashi Hatamaru, Keiichi Itonaga, Masahiro Ashida, Reiko Ida, Yoshiyuki Maekita, Takao Iguchi, Mikitaka Kitano, Masayuki Diagnostics (Basel) Article Detective flow imaging endoscopic ultrasonography (DFI-EUS) provides a new method to image and detect fine vessels and low-velocity blood flow without using ultrasound contrast agents. The aim of this study was to evaluate the utility of DFI-EUS for pancreatobiliary lesions and lymph nodes. Between January 2019 and January 2020, 53 patients who underwent DFI-EUS, e-FLOW EUS, and contrast-enhanced EUS were enrolled. The ability of DFI-EUS and e-FLOW EUS to detect vessels was compared with that of contrast-enhanced EUS. This article describes the DFI technique along with our first experience of its use for vascular assessment of pancreatobiliary lesions. Vessels were imaged in 34 pancreatic solid lesions, eight intraductal papillary mucinous neoplasms (IPMNs), seven gall bladder lesions, and four swollen lymph nodes. DFI-EUS (91%) was significantly superior to e-FLOW EUS (53%) with respect to detection of vessels (p < 0.001) and for discrimination of mural nodules from mucous clots in IPMN and gallbladder lesions from sludge (p = 0.046). Thus, DFI-EUS has the potential to become an essential tool for diagnosis and vascular assessment of various diseases. MDPI 2021-10-30 /pmc/articles/PMC8621279/ /pubmed/34829364 http://dx.doi.org/10.3390/diagnostics11112018 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Yamashita, Yasunobu
Yoshikawa, Takanori
Yamazaki, Hirofumi
Kawaji, Yuki
Tamura, Takashi
Hatamaru, Keiichi
Itonaga, Masahiro
Ashida, Reiko
Ida, Yoshiyuki
Maekita, Takao
Iguchi, Mikitaka
Kitano, Masayuki
A Novel Endoscopic Ultrasonography Imaging Technique for Depicting Microcirculation in Pancreatobiliary Lesions without the Need for Contrast-Enhancement: A Prospective Exploratory Study
title A Novel Endoscopic Ultrasonography Imaging Technique for Depicting Microcirculation in Pancreatobiliary Lesions without the Need for Contrast-Enhancement: A Prospective Exploratory Study
title_full A Novel Endoscopic Ultrasonography Imaging Technique for Depicting Microcirculation in Pancreatobiliary Lesions without the Need for Contrast-Enhancement: A Prospective Exploratory Study
title_fullStr A Novel Endoscopic Ultrasonography Imaging Technique for Depicting Microcirculation in Pancreatobiliary Lesions without the Need for Contrast-Enhancement: A Prospective Exploratory Study
title_full_unstemmed A Novel Endoscopic Ultrasonography Imaging Technique for Depicting Microcirculation in Pancreatobiliary Lesions without the Need for Contrast-Enhancement: A Prospective Exploratory Study
title_short A Novel Endoscopic Ultrasonography Imaging Technique for Depicting Microcirculation in Pancreatobiliary Lesions without the Need for Contrast-Enhancement: A Prospective Exploratory Study
title_sort novel endoscopic ultrasonography imaging technique for depicting microcirculation in pancreatobiliary lesions without the need for contrast-enhancement: a prospective exploratory study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621279/
https://www.ncbi.nlm.nih.gov/pubmed/34829364
http://dx.doi.org/10.3390/diagnostics11112018
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