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Takinib Inhibits Inflammation in Human Rheumatoid Arthritis Synovial Fibroblasts by Targeting the Janus Kinase-Signal Transducer and Activator of Transcription 3 (JAK/STAT3) Pathway

TGF β-activated kinase 1 (TAK1) is an important participant in inflammatory pathogenesis for diseases such as rheumatoid arthritis (RA) and gouty arthritis. The central position it occupies between the mitogen activated protein kinase (MAPK) and nuclear factor kappa B (NF-κB) pathways makes it an at...

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Detalles Bibliográficos
Autores principales:	Panipinto, Paul M., Singh, Anil K., Shaikh, Farheen S., Siegel, Ruby J., Chourasia, Mukesh, Ahmed, Salahuddin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621335/ https://www.ncbi.nlm.nih.gov/pubmed/34830460 http://dx.doi.org/10.3390/ijms222212580

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