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Structural Basis of Arrestin Selectivity for Active Phosphorylated G Protein-Coupled Receptors

Arrestins are a small family of proteins that bind G protein-coupled receptors (GPCRs). Arrestin binds to active phosphorylated GPCRs with higher affinity than to all other functional forms of the receptor, including inactive phosphorylated and active unphosphorylated. The selectivity of arrestins s...

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Detalles Bibliográficos
Autores principales: Karnam, Preethi C., Vishnivetskiy, Sergey A., Gurevich, Vsevolod V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621391/
https://www.ncbi.nlm.nih.gov/pubmed/34830362
http://dx.doi.org/10.3390/ijms222212481

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