Distinctive Role of the Systemic Inflammatory Profile in Non-Small-Cell Lung Cancer Younger and Elderly Patients Treated with a PD-1 Immune Checkpoint Blockade: A Real-World Retrospective Multi-Institutional Analysis

An immune checkpoint blockade with mAbs to PD-1 and PD-L1 is an expanding therapeutic option for mNSCLC patients. This treatment strategy is based on the use of mAbs able to restore the anti-tumor activity of intratumoral T cells inhibited by PD-1 binding to PD-L1/2 on tumor and inflammatory cells....

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Detalles Bibliográficos
Autores principales: Nardone, Valerio, Giannicola, Rocco, Giannarelli, Diana, Saladino, Rita Emilena, Azzarello, Domenico, Romeo, Caterina, Bianco, Giovanna, Rizzo, Maria Rosaria, Di Meo, Irene, Nesci, Antonio, Pastina, Pierpaolo, Falzea, Antonia Consuelo, Caracciolo, Daniele, Reginelli, Alfonso, Caraglia, Michele, Luce, Amalia, Mutti, Luciano, Giordano, Antonio, Cappabianca, Salvatore, Pirtoli, Luigi, Barbieri, Vito, Tassone, Pierfrancesco, Tagliaferri, Pierosandro, Correale, Pierpaolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621400/
https://www.ncbi.nlm.nih.gov/pubmed/34833111
http://dx.doi.org/10.3390/life11111235

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