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Plant-Based versus Animal-Based Low Protein Diets in the Management of Chronic Kidney Disease
Recent data reiterate low-protein diets (LPDs) as cornerstones in the conservative management of chronic kidney disease (CKD). The reduction in proteinuria, better blood pressure control and the reduction in the rate of decline in kidney function with LPDs were reported, both in non-diabetics and di...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621419/ https://www.ncbi.nlm.nih.gov/pubmed/34835976 http://dx.doi.org/10.3390/nu13113721 |
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author | Mocanu, Carmen-Antonia Simionescu, Tudor Petrisor Mocanu, Andreea Elena Garneata, Liliana |
author_facet | Mocanu, Carmen-Antonia Simionescu, Tudor Petrisor Mocanu, Andreea Elena Garneata, Liliana |
author_sort | Mocanu, Carmen-Antonia |
collection | PubMed |
description | Recent data reiterate low-protein diets (LPDs) as cornerstones in the conservative management of chronic kidney disease (CKD). The reduction in proteinuria, better blood pressure control and the reduction in the rate of decline in kidney function with LPDs were reported, both in non-diabetics and diabetics patients. Supplemented, vegetarian, very-low-protein diets (sVLPD, 0.3 g/kg-day) could postpone kidney replacement therapy (KRT) initiation, mainly through the better control of metabolic disorders of advanced CKD in non-diabetic patients. Plant-based diets could ameliorate gut microbiota and appear to be superior to mixed hypoproteic diets in treating advanced CKD: better control of nitrogen balance, acid-base metabolism and bone mineral disorders. Vegetarian diets generate fewer uremic toxins and reduce salt intake and acid overload. At the same time, they can improve lipid metabolism, providing a high ratio of unsaturated to saturated fatty acids, as well as insulin resistance. |
format | Online Article Text |
id | pubmed-8621419 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86214192021-11-27 Plant-Based versus Animal-Based Low Protein Diets in the Management of Chronic Kidney Disease Mocanu, Carmen-Antonia Simionescu, Tudor Petrisor Mocanu, Andreea Elena Garneata, Liliana Nutrients Review Recent data reiterate low-protein diets (LPDs) as cornerstones in the conservative management of chronic kidney disease (CKD). The reduction in proteinuria, better blood pressure control and the reduction in the rate of decline in kidney function with LPDs were reported, both in non-diabetics and diabetics patients. Supplemented, vegetarian, very-low-protein diets (sVLPD, 0.3 g/kg-day) could postpone kidney replacement therapy (KRT) initiation, mainly through the better control of metabolic disorders of advanced CKD in non-diabetic patients. Plant-based diets could ameliorate gut microbiota and appear to be superior to mixed hypoproteic diets in treating advanced CKD: better control of nitrogen balance, acid-base metabolism and bone mineral disorders. Vegetarian diets generate fewer uremic toxins and reduce salt intake and acid overload. At the same time, they can improve lipid metabolism, providing a high ratio of unsaturated to saturated fatty acids, as well as insulin resistance. MDPI 2021-10-22 /pmc/articles/PMC8621419/ /pubmed/34835976 http://dx.doi.org/10.3390/nu13113721 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Mocanu, Carmen-Antonia Simionescu, Tudor Petrisor Mocanu, Andreea Elena Garneata, Liliana Plant-Based versus Animal-Based Low Protein Diets in the Management of Chronic Kidney Disease |
title | Plant-Based versus Animal-Based Low Protein Diets in the Management of Chronic Kidney Disease |
title_full | Plant-Based versus Animal-Based Low Protein Diets in the Management of Chronic Kidney Disease |
title_fullStr | Plant-Based versus Animal-Based Low Protein Diets in the Management of Chronic Kidney Disease |
title_full_unstemmed | Plant-Based versus Animal-Based Low Protein Diets in the Management of Chronic Kidney Disease |
title_short | Plant-Based versus Animal-Based Low Protein Diets in the Management of Chronic Kidney Disease |
title_sort | plant-based versus animal-based low protein diets in the management of chronic kidney disease |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621419/ https://www.ncbi.nlm.nih.gov/pubmed/34835976 http://dx.doi.org/10.3390/nu13113721 |
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