Cargando…
Dual Role of SIRT1 in Autophagy and Lipid Metabolism Regulation in Osteoarthritic Chondrocytes
Background and Objectives: Osteoarthritis (OA) is one of the most common and highly prevalent types of arthritis, also considered a multiphenotypic disease with a strong metabolic component. Ageing is the primary risk factor for OA, while the age-related decline in autophagic activity affects cell f...
Autores principales: | Papageorgiou, Aliki-Alexandra, Goutas, Andreas, Trachana, Varvara, Tsezou, Aspasia |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621567/ https://www.ncbi.nlm.nih.gov/pubmed/34833421 http://dx.doi.org/10.3390/medicina57111203 |
Ejemplares similares
-
Oxidative Stress Response Is Mediated by Overexpression and Spatiotemporal Regulation of Caveolin-1
por: Goutas, Andreas, et al.
Publicado: (2020) -
Involvement of SOX-9 and FGF-23 in RUNX-2 regulation in osteoarthritic chondrocytes
por: Orfanidou, Timoklia, et al.
Publicado: (2009) -
MicroRNA-33a regulates cholesterol synthesis and cholesterol efflux-related genes in osteoarthritic chondrocytes
por: Kostopoulou, Fotini, et al.
Publicado: (2015) -
DNA methylation regulates sclerostin (SOST) expression in osteoarthritic chondrocytes by bone morphogenetic protein 2 (BMP-2) induced changes in Smads binding affinity to the CpG region of SOST promoter
por: Papathanasiou, Ioanna, et al.
Publicado: (2015) -
Stem cells' centrosomes: How can organelles identified 130 years ago contribute to the future of regenerative medicine?
por: Goutas, Andreas, et al.
Publicado: (2021)