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Dual Role of SIRT1 in Autophagy and Lipid Metabolism Regulation in Osteoarthritic Chondrocytes

Background and Objectives: Osteoarthritis (OA) is one of the most common and highly prevalent types of arthritis, also considered a multiphenotypic disease with a strong metabolic component. Ageing is the primary risk factor for OA, while the age-related decline in autophagic activity affects cell f...

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Detalles Bibliográficos
Autores principales: Papageorgiou, Aliki-Alexandra, Goutas, Andreas, Trachana, Varvara, Tsezou, Aspasia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621567/
https://www.ncbi.nlm.nih.gov/pubmed/34833421
http://dx.doi.org/10.3390/medicina57111203

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