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Prevalence of Zinc Deficiency in Healthy 1–3-Year-Old Children from Three Western European Countries
Zinc deficiency (ZnD) has adverse health consequences such as stunted growth. Since young children have an increased risk of developing ZnD, it is important to determine its prevalence and associated factors in this population. However, only a few studies have reported on ZnD prevalence in young chi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621620/ https://www.ncbi.nlm.nih.gov/pubmed/34835970 http://dx.doi.org/10.3390/nu13113713 |
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author | Vreugdenhil, Mirjam Akkermans, Marjolijn D. van der Merwe, Liandré F. van Elburg, Ruurd M. van Goudoever, Johannes B. Brus, Frank |
author_facet | Vreugdenhil, Mirjam Akkermans, Marjolijn D. van der Merwe, Liandré F. van Elburg, Ruurd M. van Goudoever, Johannes B. Brus, Frank |
author_sort | Vreugdenhil, Mirjam |
collection | PubMed |
description | Zinc deficiency (ZnD) has adverse health consequences such as stunted growth. Since young children have an increased risk of developing ZnD, it is important to determine its prevalence and associated factors in this population. However, only a few studies have reported on ZnD prevalence in young children from Western high-income countries. This study evaluated ZnD prevalence and associated factors, including dietary Zn intake, in healthy 1–3-year-old children from Western European, high-income countries. ZnD was defined as serum Zn concentration <9.9 µmol/L. A total of 278 children were included with a median age of 1.7 years (Q1–Q3: 1.2–2.3). The median Zn concentration was 11.0 µmol/L (Q1–Q3: 9.0–12.2), and ZnD prevalence was 31.3%. No significant differences were observed in the socio-economic characteristics between children with and without ZnD. Dietary Zn intake was not associated with ZnD. ZnD is common in healthy 1–3-year-old children from Western European countries. However, the use of currently available cut-off values defining ZnD in young children has its limitations since these are largely based on reference values in older children. Moreover, these values were not evaluated in relation to health consequences, warranting further research. |
format | Online Article Text |
id | pubmed-8621620 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86216202021-11-27 Prevalence of Zinc Deficiency in Healthy 1–3-Year-Old Children from Three Western European Countries Vreugdenhil, Mirjam Akkermans, Marjolijn D. van der Merwe, Liandré F. van Elburg, Ruurd M. van Goudoever, Johannes B. Brus, Frank Nutrients Article Zinc deficiency (ZnD) has adverse health consequences such as stunted growth. Since young children have an increased risk of developing ZnD, it is important to determine its prevalence and associated factors in this population. However, only a few studies have reported on ZnD prevalence in young children from Western high-income countries. This study evaluated ZnD prevalence and associated factors, including dietary Zn intake, in healthy 1–3-year-old children from Western European, high-income countries. ZnD was defined as serum Zn concentration <9.9 µmol/L. A total of 278 children were included with a median age of 1.7 years (Q1–Q3: 1.2–2.3). The median Zn concentration was 11.0 µmol/L (Q1–Q3: 9.0–12.2), and ZnD prevalence was 31.3%. No significant differences were observed in the socio-economic characteristics between children with and without ZnD. Dietary Zn intake was not associated with ZnD. ZnD is common in healthy 1–3-year-old children from Western European countries. However, the use of currently available cut-off values defining ZnD in young children has its limitations since these are largely based on reference values in older children. Moreover, these values were not evaluated in relation to health consequences, warranting further research. MDPI 2021-10-22 /pmc/articles/PMC8621620/ /pubmed/34835970 http://dx.doi.org/10.3390/nu13113713 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Vreugdenhil, Mirjam Akkermans, Marjolijn D. van der Merwe, Liandré F. van Elburg, Ruurd M. van Goudoever, Johannes B. Brus, Frank Prevalence of Zinc Deficiency in Healthy 1–3-Year-Old Children from Three Western European Countries |
title | Prevalence of Zinc Deficiency in Healthy 1–3-Year-Old Children from Three Western European Countries |
title_full | Prevalence of Zinc Deficiency in Healthy 1–3-Year-Old Children from Three Western European Countries |
title_fullStr | Prevalence of Zinc Deficiency in Healthy 1–3-Year-Old Children from Three Western European Countries |
title_full_unstemmed | Prevalence of Zinc Deficiency in Healthy 1–3-Year-Old Children from Three Western European Countries |
title_short | Prevalence of Zinc Deficiency in Healthy 1–3-Year-Old Children from Three Western European Countries |
title_sort | prevalence of zinc deficiency in healthy 1–3-year-old children from three western european countries |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621620/ https://www.ncbi.nlm.nih.gov/pubmed/34835970 http://dx.doi.org/10.3390/nu13113713 |
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