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Prevalence of Zinc Deficiency in Healthy 1–3-Year-Old Children from Three Western European Countries

Zinc deficiency (ZnD) has adverse health consequences such as stunted growth. Since young children have an increased risk of developing ZnD, it is important to determine its prevalence and associated factors in this population. However, only a few studies have reported on ZnD prevalence in young chi...

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Autores principales: Vreugdenhil, Mirjam, Akkermans, Marjolijn D., van der Merwe, Liandré F., van Elburg, Ruurd M., van Goudoever, Johannes B., Brus, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621620/
https://www.ncbi.nlm.nih.gov/pubmed/34835970
http://dx.doi.org/10.3390/nu13113713
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author Vreugdenhil, Mirjam
Akkermans, Marjolijn D.
van der Merwe, Liandré F.
van Elburg, Ruurd M.
van Goudoever, Johannes B.
Brus, Frank
author_facet Vreugdenhil, Mirjam
Akkermans, Marjolijn D.
van der Merwe, Liandré F.
van Elburg, Ruurd M.
van Goudoever, Johannes B.
Brus, Frank
author_sort Vreugdenhil, Mirjam
collection PubMed
description Zinc deficiency (ZnD) has adverse health consequences such as stunted growth. Since young children have an increased risk of developing ZnD, it is important to determine its prevalence and associated factors in this population. However, only a few studies have reported on ZnD prevalence in young children from Western high-income countries. This study evaluated ZnD prevalence and associated factors, including dietary Zn intake, in healthy 1–3-year-old children from Western European, high-income countries. ZnD was defined as serum Zn concentration <9.9 µmol/L. A total of 278 children were included with a median age of 1.7 years (Q1–Q3: 1.2–2.3). The median Zn concentration was 11.0 µmol/L (Q1–Q3: 9.0–12.2), and ZnD prevalence was 31.3%. No significant differences were observed in the socio-economic characteristics between children with and without ZnD. Dietary Zn intake was not associated with ZnD. ZnD is common in healthy 1–3-year-old children from Western European countries. However, the use of currently available cut-off values defining ZnD in young children has its limitations since these are largely based on reference values in older children. Moreover, these values were not evaluated in relation to health consequences, warranting further research.
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spelling pubmed-86216202021-11-27 Prevalence of Zinc Deficiency in Healthy 1–3-Year-Old Children from Three Western European Countries Vreugdenhil, Mirjam Akkermans, Marjolijn D. van der Merwe, Liandré F. van Elburg, Ruurd M. van Goudoever, Johannes B. Brus, Frank Nutrients Article Zinc deficiency (ZnD) has adverse health consequences such as stunted growth. Since young children have an increased risk of developing ZnD, it is important to determine its prevalence and associated factors in this population. However, only a few studies have reported on ZnD prevalence in young children from Western high-income countries. This study evaluated ZnD prevalence and associated factors, including dietary Zn intake, in healthy 1–3-year-old children from Western European, high-income countries. ZnD was defined as serum Zn concentration <9.9 µmol/L. A total of 278 children were included with a median age of 1.7 years (Q1–Q3: 1.2–2.3). The median Zn concentration was 11.0 µmol/L (Q1–Q3: 9.0–12.2), and ZnD prevalence was 31.3%. No significant differences were observed in the socio-economic characteristics between children with and without ZnD. Dietary Zn intake was not associated with ZnD. ZnD is common in healthy 1–3-year-old children from Western European countries. However, the use of currently available cut-off values defining ZnD in young children has its limitations since these are largely based on reference values in older children. Moreover, these values were not evaluated in relation to health consequences, warranting further research. MDPI 2021-10-22 /pmc/articles/PMC8621620/ /pubmed/34835970 http://dx.doi.org/10.3390/nu13113713 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Vreugdenhil, Mirjam
Akkermans, Marjolijn D.
van der Merwe, Liandré F.
van Elburg, Ruurd M.
van Goudoever, Johannes B.
Brus, Frank
Prevalence of Zinc Deficiency in Healthy 1–3-Year-Old Children from Three Western European Countries
title Prevalence of Zinc Deficiency in Healthy 1–3-Year-Old Children from Three Western European Countries
title_full Prevalence of Zinc Deficiency in Healthy 1–3-Year-Old Children from Three Western European Countries
title_fullStr Prevalence of Zinc Deficiency in Healthy 1–3-Year-Old Children from Three Western European Countries
title_full_unstemmed Prevalence of Zinc Deficiency in Healthy 1–3-Year-Old Children from Three Western European Countries
title_short Prevalence of Zinc Deficiency in Healthy 1–3-Year-Old Children from Three Western European Countries
title_sort prevalence of zinc deficiency in healthy 1–3-year-old children from three western european countries
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621620/
https://www.ncbi.nlm.nih.gov/pubmed/34835970
http://dx.doi.org/10.3390/nu13113713
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