Towards the Development of a Female Animal Model of T1DM Using Hyaluronic Acid Nanocoated Cell Transplantation: Refinements and Considerations for Future Protocols

Female mice (Black 6 strain) (C57BL/6) aged 6 weeks were subject to low dose streptozotocin (STZ) treatment for five consecutive days to mimic type 1 diabetes mellitus (T1DM) with insulitis. At two weeks after STZ injections, evaluation of the elevated glucose levels was used to confirm diabetes. Th...

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Detalles Bibliográficos
Autores principales: Zamboni, Fernanda, Cengiz, Ibrahim F., Barbosa, Ana M., Castro, Antonio G., Reis, Rui L., Oliveira, Joaquim M., Collins, Maurice N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621706/
https://www.ncbi.nlm.nih.gov/pubmed/34834340
http://dx.doi.org/10.3390/pharmaceutics13111925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621706/
https://www.ncbi.nlm.nih.gov/pubmed/34834340
http://dx.doi.org/10.3390/pharmaceutics13111925

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