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The Deleterious Effects of Shiga Toxin Type 2 Are Neutralized In Vitro by FabF8:Stx2 Recombinant Monoclonal Antibody

Hemolytic Uremic Syndrome (HUS) associated with Shiga-toxigenic Escherichia coli (STEC) infections is the principal cause of acute renal injury in pediatric age groups. Shiga toxin type 2 (Stx2) has in vitro cytotoxic effects on kidney cells, including human glomerular endothelial (HGEC) and Vero ce...

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Detalles Bibliográficos
Autores principales: Luz, Daniela, Gómez, Fernando D., Ferreira, Raíssa L., Melo, Bruna S., Guth, Beatriz E. C., Quintilio, Wagner, Moro, Ana Maria, Presta, Agostina, Sacerdoti, Flavia, Ibarra, Cristina, Chen, Gang, Sidhu, Sachdev S., Amaral, María Marta, Piazza, Roxane M. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621789/
https://www.ncbi.nlm.nih.gov/pubmed/34822608
http://dx.doi.org/10.3390/toxins13110825

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