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Synergistic Mutations of LRP6 and WNT10A in Familial Tooth Agenesis

Familial tooth agenesis (FTA), distinguished by developmental failure of selected teeth, is one of the most prevalent craniofacial anomalies in humans. Mutations in genes involved in WNT/β-catenin signaling, including AXIN2 WNT10A, WNT10B, LRP6, and KREMEN1, are known to cause FTA. However, mutation...

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Detalles Bibliográficos
Autores principales:	Chu, Kuan-Yu, Wang, Yin-Lin, Chou, Yu-Ren, Chen, Jung-Tsu, Wang, Yi-Ping, Simmer, James P., Hu, Jan C.-C., Wang, Shih-Kai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621929/ https://www.ncbi.nlm.nih.gov/pubmed/34834569 http://dx.doi.org/10.3390/jpm11111217

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