Cargando…
Model Balancing: A Search for In-Vivo Kinetic Constants and Consistent Metabolic States
Enzyme kinetic constants in vivo are largely unknown, which limits the construction of large metabolic models. Given measured metabolic fluxes, metabolite concentrations, and enzyme concentrations, these constants may be inferred by model fitting, but the estimation problems are hard to solve if mod...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8621975/ https://www.ncbi.nlm.nih.gov/pubmed/34822407 http://dx.doi.org/10.3390/metabo11110749 |