Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies and Leucovorin (Folinic Acid) Treatment in Autism Spectrum Disorders: A Systematic Review and Meta-Analysis

The cerebral folate receptor alpha (FRα) transports 5-methyltetrahydrofolate (5-MTHF) into the brain; low 5-MTHF in the brain causes cerebral folate deficiency (CFD). CFD has been associated with autism spectrum disorders (ASD) and is treated with d,l-leucovorin (folinic acid). One cause of CFD is a...

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Detalles Bibliográficos
Autores principales: Rossignol, Daniel A., Frye, Richard E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622150/
https://www.ncbi.nlm.nih.gov/pubmed/34834493
http://dx.doi.org/10.3390/jpm11111141

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622150/
https://www.ncbi.nlm.nih.gov/pubmed/34834493
http://dx.doi.org/10.3390/jpm11111141

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