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Feline Demodicosis Case Report—First Molecular Characterization of Demodex Mites in Romania
Cat demodicosis is uncommon to rare, and is caused by Demodex cati, Demodex gatoi and another unnamed species. The investigated patient was a mix-breed, 10-year-old feline with no dermatological history. Alopecia, erythema, minor erosions and ulcerations and crusts, associated with pruritus and self...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622192/ https://www.ncbi.nlm.nih.gov/pubmed/34832631 http://dx.doi.org/10.3390/pathogens10111474 |
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author | Ilie, Marius Stelian Imre, Mirela Giubega, Simona Luca, Iasmina Florea, Tiana Morariu, Sorin |
author_facet | Ilie, Marius Stelian Imre, Mirela Giubega, Simona Luca, Iasmina Florea, Tiana Morariu, Sorin |
author_sort | Ilie, Marius Stelian |
collection | PubMed |
description | Cat demodicosis is uncommon to rare, and is caused by Demodex cati, Demodex gatoi and another unnamed species. The investigated patient was a mix-breed, 10-year-old feline with no dermatological history. Alopecia, erythema, minor erosions and ulcerations and crusts, associated with pruritus and self-trauma, were observed on the head. Dark, agglutinated cerumen was also present in the external ear canal. The agent causing the skin condition in the feline patient was identified as being a Demodex genus mite, based on the specific, morphological characteristics noticed upon the microscopic examination of deep skin scrapes. Biological samples were collected from the patient with to perform a PCR assay for clear species-determination and morphological assessment. PCR amplification of DNA extracted from the Demodex mites produced a single band of ~330 bp, indicating the presence of the D. cati species. The acaricidal treatment consisted of topical treatment using a fluralaner and moxidectin-based spot-on. Upon follow-up appointments, scheduled three times at a monthly interval, the patient failed to provide a positive result upon deep skin scrapes. The negative scrapes were also accompanied by the complete resolution of the existing lesions. In conclusion, this is the first molecular study to highlight the presence of Demodex cati within the feline population of Romania, and the fluralaner-moxidectin spot-on therapy has led to a complete recovery of the feline patient affected by feline demodicosis. |
format | Online Article Text |
id | pubmed-8622192 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-86221922021-11-27 Feline Demodicosis Case Report—First Molecular Characterization of Demodex Mites in Romania Ilie, Marius Stelian Imre, Mirela Giubega, Simona Luca, Iasmina Florea, Tiana Morariu, Sorin Pathogens Case Report Cat demodicosis is uncommon to rare, and is caused by Demodex cati, Demodex gatoi and another unnamed species. The investigated patient was a mix-breed, 10-year-old feline with no dermatological history. Alopecia, erythema, minor erosions and ulcerations and crusts, associated with pruritus and self-trauma, were observed on the head. Dark, agglutinated cerumen was also present in the external ear canal. The agent causing the skin condition in the feline patient was identified as being a Demodex genus mite, based on the specific, morphological characteristics noticed upon the microscopic examination of deep skin scrapes. Biological samples were collected from the patient with to perform a PCR assay for clear species-determination and morphological assessment. PCR amplification of DNA extracted from the Demodex mites produced a single band of ~330 bp, indicating the presence of the D. cati species. The acaricidal treatment consisted of topical treatment using a fluralaner and moxidectin-based spot-on. Upon follow-up appointments, scheduled three times at a monthly interval, the patient failed to provide a positive result upon deep skin scrapes. The negative scrapes were also accompanied by the complete resolution of the existing lesions. In conclusion, this is the first molecular study to highlight the presence of Demodex cati within the feline population of Romania, and the fluralaner-moxidectin spot-on therapy has led to a complete recovery of the feline patient affected by feline demodicosis. MDPI 2021-11-12 /pmc/articles/PMC8622192/ /pubmed/34832631 http://dx.doi.org/10.3390/pathogens10111474 Text en © 2021 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Ilie, Marius Stelian Imre, Mirela Giubega, Simona Luca, Iasmina Florea, Tiana Morariu, Sorin Feline Demodicosis Case Report—First Molecular Characterization of Demodex Mites in Romania |
title | Feline Demodicosis Case Report—First Molecular Characterization of Demodex Mites in Romania |
title_full | Feline Demodicosis Case Report—First Molecular Characterization of Demodex Mites in Romania |
title_fullStr | Feline Demodicosis Case Report—First Molecular Characterization of Demodex Mites in Romania |
title_full_unstemmed | Feline Demodicosis Case Report—First Molecular Characterization of Demodex Mites in Romania |
title_short | Feline Demodicosis Case Report—First Molecular Characterization of Demodex Mites in Romania |
title_sort | feline demodicosis case report—first molecular characterization of demodex mites in romania |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8622192/ https://www.ncbi.nlm.nih.gov/pubmed/34832631 http://dx.doi.org/10.3390/pathogens10111474 |
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